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SML2602

Sigma-Aldrich

CW3388

≥98% (HPLC)

Synonym(s):

1-([1,1′-Biphenyl]-4-ylmethyl)octahydro-azocine

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About This Item

Empirical Formula (Hill Notation):
C20H25N
CAS Number:
414881-01-9
Molecular Weight:
279.42
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

oil

color

colorless to yellow

storage temp.

2-8°C

SMILES string

N3(CCCCCCC3)Cc1ccc(cc1)c2ccccc2

InChI

1S/C20H25N/c1-2-7-15-21(16-8-3-1)17-18-11-13-20(14-12-18)19-9-5-4-6-10-19/h4-6,9-14H,1-3,7-8,15-17H2

InChI key

BTDKOFMWYIXWST-UHFFFAOYSA-N

Biochem/physiol Actions

CW3388 is a cell active and highly potent enhancer of oligodendrocyte formation. CW3388 potently inhibits the cholesterol biosynthesis enzyme Δ8,7-sterol isomerase (EBP). It promotes myelination in vitro.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000193014

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Dharmaraja Allimuthu et al.
Cell chemical biology, 26(4), 593-599 (2019-02-19)
Small molecules that promote oligodendrocyte formation have been identified in "drug repurposing" screens to nominate candidate therapeutics for diseases in which myelin is lost, including multiple sclerosis. We recently reported that many such molecules enhance oligodendrocyte formation not by their

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