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SMB00111

Sigma-Aldrich

12-Methoxycarnosic acid

≥95% (LC/MS-ELSD)

Synonym(s):

Carnosic acid 12-methyl ether

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About This Item

Empirical Formula (Hill Notation):
C21H30O4
CAS Number:
Molecular Weight:
346.46
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

COc1c(O)c2c(CC[C@H]3C(C)(C)CCC[C@]23C(O)=O)cc1C(C)C

InChI

1S/C21H30O4/c1-12(2)14-11-13-7-8-15-20(3,4)9-6-10-21(15,19(23)24)16(13)17(22)18(14)25-5/h11-12,15,22H,6-10H2,1-5H3,(H,23,24)/t15-,21+/m0/s1

InChI key

QQNSARJGBPMQDI-YCRPNKLZSA-N

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General description

12-Methoxycarnosic acid is a natural product derived from a plant source. It is a diterpene and can be sourced from Salvia microphylla.

Application

12-Methoxycarnosic acid has been used as a standardin high performance liquid chromatography (HPLC),to identify major constituents in rosemary leaves.

Biochem/physiol Actions

12-Methoxycarnosic acid is known to possess in vitro antileishmanial activity. It also functions as an antioxidant.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Constituents of Salvia microphylla
Aydo?mus Z, et al.
Natural product research, 20(8) (2006)
Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth.(Lamiaceae)
Mokoka TA, et al.
South African Journal of botony, 90(9) (2014)
Supercritical fluid extracts of rosemary leaves exhibit potent anti-inflammation and anti-tumor effects
Peng CH, et al.
Bioscience, Biotechnology, and Biochemistry, 71(9) (2007)
Promotion of hair growth by Rosmarinus officinalis leaf extract
Murata K, et al.
Phytotherapy Research, 27(2) (2013)

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