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Key Documents

MAK553

Sigma-Aldrich

Fluorimetric cADP-Ribose Assay Kit

sufficient for 100 fluorometric tests

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About This Item

UNSPSC Code:
41116104
NACRES:
NA.84

Pricing and availability is not currently available.

detection method

fluorometric

relevant disease(s)

genitourinary disorders; neurological disorders; cardiovascular diseases; cancer

shipped in

dry ice

storage temp.

−20°C

General description

cADP-ribose (cADPR) is a novel Ca2+ messenger derived from NAD+. ADP-riboxyl cyclase (ADPRC) catalyzes the synthesis of cADPR from NAD+, but the reaction can be reversed in the presence of high concentration of nicotinamide, producing NAD+ from cADPR stoichiometrically. The resultant NAD+ can be detected by the NAD probe. This makes monitoring cADPR in tissues and cell cultures possible in the low nM range. The NAD+ detection using NAD probe is specific to NAD+ and has no reaction to NADH. This assay can be performed in a convenient 96-well or 384-well microplate.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


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