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EMU017471

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Lonp1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

ACACATCCAAGGAGGTGCTCATGGTGGAGGTTGAGAATGTAGCCCATGAATACTTCCAGGTCACAGAGGAAGTGAAGGCCCTGACTGCAGAGATTGTGAAGACCATCCGGGATATCATCGCCTTGAACCCTCTGTACAGAGAGTCCGTGCTGCAGATGATGCAGGCAGGCCAGCGTGTGGTGGACAACCCCATCTACTTGAGCGACATGGGTGCGGCACTCACTGGGGCGGAGTCCCATGAGCTGCAAGATGTTCTGGAAGAGACCAACATCCTTAAGCGGCTCTATAAGGCCCTGTCTCTCTTGAAGAAGGAGTTTGAGTTGAGCAAGCTTCAGCAACGCCCAGGCCGTGAGGTAGAGGAGAAGATCAAGCAGACACACAGGAAGTACCTGCTGCAGGAGCAGTTGAAGATCATCAAGAAGGAATTGGGGCT

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Marie Lagouge et al.
PLoS genetics, 11(8), e1005423-e1005423 (2015-08-08)
We have studied the in vivo role of SLIRP in regulation of mitochondrial DNA (mtDNA) gene expression and show here that it stabilizes its interacting partner protein LRPPRC by protecting it from degradation. Although SLIRP is completely dependent on LRPPRC

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