C3130

Cortisone 21-acetate

≥99%

• Synonym(s): 17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 21-Acetoxy-4-pregnen-17α-ol-3,11,20-trione, 4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate
• Empirical Formula (Hill Notation): C₂₃H₃₀O₆
• CAS Number: 50-04-4
• Molecular Weight: 402.48
• Beilstein: 2067543
• EC Number: 200-006-5
• MDL number: MFCD00003609
• UNSPSC Code: 51111800
• PubChem Substance ID: 24278306
• NACRES: NA.77

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• sterility: non-sterile
• Assay: ≥99%
• form: powder
• mp: 237-240 °C (lit.)
• solubility: chloroform: 50 mg/mL, clear, colorless to faintly yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])C(=O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1
• InChI key: ITRJWOMZKQRYTA-RFZYENFJSA-N
• Gene Information: human ... FNTA(2339) , NR3C1(2908)

Description

General description

Cortisone 21-acetate is a prodrug, which has glucocorticoid and mineralocorticoid properties. It is used as a therapeutic option for glucocorticoid replacement.

Application

Cortisone 21-acetate has been used to study its effects in metastasis and phagocytic activity.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H361d
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves