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A7165

Sigma-Aldrich

1,5-Anhydro-D-sorbitol

crystalline, ≥98.0% (TLC)

Synonym(s):

1,5-Anhydro-D-glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H12O5
CAS Number:
154-58-5
Molecular Weight:
164.16
EC Number:
205-829-3
MDL number:
MFCD00067386
UNSPSC Code:
12352201
PubChem Substance ID:
24891181
NACRES:
NA.25

Quality Level

200

Assay

≥98.0% (TLC)

form

crystalline

color

white

solubility

water: 49.00-51.00 mg/mL, clear, colorless

SMILES string

OCC1OCC(O)C(O)C1O

InChI

1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2

InChI key

MPCAJMNYNOGXPB-UHFFFAOYSA-N

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Application

1,5-Anhydro-D-sorbitol, a cyclic polyol, is a metabolic product of 1,5 anhydro-D-fructose. 1,5-Anhydro-D-sorbitol is used as a reference in analytical procedures that assess the metabolism of 1,5 anhydro-D-fructose, a food supplement with potential benefits as an antioxidant, antimicrobial, and antidiabetic agent.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Masaya Sakamoto et al.
Cardiovascular diabetology, 11, 92-92 (2012-08-08)
No previous studies have compared the DPP-4 inhibitors vildagliptin and sitagliptin in terms of blood glucose levels using continuous glucose monitoring (CGM) and cardiovascular parameters. Twenty patients with type 2 diabetes mellitus were randomly allocated to groups who received vildagliptin
Roy Beck et al.
Pediatric diabetes, 12(8), 690-695 (2011-04-19)
To describe the interrelationships of glycemic control measures: hemoglobin A1c (HbA1c), glycated albumin, fructosamine, 1,5-anhydroglucitrol (1,5-AG), and continuous glucose monitoring (CGM) in children and adolescents with type 1 diabetes. In total, 26 subjects of age 4-17 had HbA1c measurement followed
W J Kim et al.
Diabetic medicine : a journal of the British Diabetic Association, 29(9), 1184-1190 (2012-02-16)
To determine whether there is a relationship between 1,5-anhydroglucitol (1,5-AG), a marker of postprandial hyperglycaemia and glycaemic variability, and the presence of diabetic retinopathy and albuminuria in patients with Type 2 diabetes. Five hundred and sixty-seven patients with Type 2
Hermann Koepsell
Pflugers Archiv : European journal of physiology, 472(9), 1299-1343 (2020-08-14)
Energy demand of neurons in brain that is covered by glucose supply from the blood is ensured by glucose transporters in capillaries and brain cells. In brain, the facilitative diffusion glucose transporters GLUT1-6 and GLUT8, and the Na+-D-glucose cotransporters SGLT1
Won Jun Kim et al.
Diabetes care, 35(2), 281-286 (2012-01-03)
To assess the relationship between 1,5-anhydroglucitol (AG) levels, which are a marker of glycemic control, and stages of chronic kidney disease (CKD). This was a cross-sectional study with 269 subjects with type 2 diabetes who were divided into four groups
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