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87333

Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 600

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24888888
NACRES:
NA.26

Quality Level

100
200

product line

BioUltra

form

liquid (or viscous liquid or paste)

mol wt

Mr 570-630

impurities

insoluble matter:, passes filter test
≤0.002% peroxides (as H2O2)

refractive index

n20/D 1.469

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

17-22 °C (lit.)

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

density

1.13 g/mL at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤500 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Application


  • Label-Free Quantification Proteomics for the Identification of Mesenchymal Stromal Cell Matrisome Inside 3D Poly(Ethylene Glycol) Hydrogels.: This research highlights the application of PEG hydrogels in studying mesenchymal stromal cell environments using label-free quantification proteomics, providing insights into cell-matrix interactions and tissue engineering (Devaud et al., 2018).

  • Bioglass Activated Albumin Hydrogels for Wound Healing.: The study presents PEG-based bioglass activated albumin hydrogels as effective materials for enhancing wound healing processes, demonstrating their biocompatibility and regenerative potential (Zhou et al., 2018).

  • Doxorubicin and Paclitaxel Carried by Methoxy Poly(ethylene glycol)-Poly(lactide-co-glycolide) is Superior than Traditional Drug-Delivery Methods.: This article discusses the superiority of PEGylated drug delivery systems over conventional methods in terms of efficacy and reduced side effects for cancer treatments (Hu et al., 2018).

  • Dental Pulp Stem Cell-Derived Chondrogenic Cells Demonstrate Differential Cell Motility in Type I and Type II Collagen Hydrogels.: The research explores the differential motility of stem cell-derived chondrogenic cells in PEG-modified collagen hydrogels, providing insights for regenerative medicine applications (Yao and Flynn, 2018).

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

281.5 °F - closed cup

Flash Point(C)

138.6 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
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