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46102

Supelco

Fludioxonil

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C12H6F2N2O2
CAS Number:
Molecular Weight:
248.19
Beilstein:
8393936
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

application(s)

agriculture
environmental

format

neat

SMILES string

FC1(F)Oc2cccc(c2O1)-c3c[nH]cc3C#N

InChI

1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H

InChI key

MUJOIMFVNIBMKC-UHFFFAOYSA-N

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Application

  • Fludioxonil fungicide in agricultural biotech: Fludioxonil′s effectiveness against the two-component histidine kinase Bos1 in Botrytis cinerea was explored, revealing its binding mode and molecular mechanism. This research underscores its critical role as a fungicide in agricultural biotechnology, providing insights that could lead to improved crop protection strategies (Yin et al., 2024).
  • Fludioxonil biochemical research for pathogen resistance: The study on Fusarium species causing soybean root rot examined the genetic basis of differing sensitivities to DMI fungicides, including fludioxonil. This contributes to a deeper understanding of fungal resistance mechanisms, enhancing the development of more effective fungicidal treatments (Zhang et al., 2024).
  • Fludioxonil antifungal properties in plant disease control: Research characterized fludioxonil and phenamacril dual resistant mutants of Fusarium graminearum, highlighting fludioxonil′s critical role in managing resistance in pathogens and its ongoing relevance in managing crop diseases (Wen et al., 2024).

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jennifer N Apell et al.
Environmental science & technology, 53(19), 11240-11250 (2019-09-06)
Fludioxonil is a pyrrole-containing pesticide whose registration as a plant protection product is currently under review in the United States and Europe. There are concerns over its potential persistence and toxicity in the aquatic environment; however, the pyrrole moiety represents
Anita Dongo et al.
Applied and environmental microbiology, 75(1), 127-134 (2008-11-18)
We have shown that the plant pathogen Alternaria brassicicola exhibited very high susceptibility to ambruticin VS4 and to a lesser extent to the phenylpyrrole fungicide fludioxonil. These compounds are both derived from natural bacterial metabolites with antifungal properties and are
Chengwei Sang et al.
Pesticide biochemistry and physiology, 147, 110-118 (2018-06-24)
Botrytis cinerea has a high risk of developing resistance to fungicides. Fludioxonil, belonging to phenylpyrroles, has been used for more than three decades, however, only few cases of field resistance against phenylpyrroles have been reported. In this study, the highly
Roger R Lew
Fungal genetics and biology : FG & B, 47(8), 721-726 (2010-06-16)
The internal hydrostatic pressure (turgor) of the filamentous fungus Neurospora crassa is regulated at about 400-500 kiloPascals, primarily by an osmotic MAP kinase cascade which activates ion uptake from the extracellular medium and glycerol synthesis. In the absence of hyperosmotic
Kentaro Furukawa et al.
FEBS letters, 586(16), 2417-2422 (2012-06-13)
The fungicide fludioxonil is used to control plant-pathogenic fungi by causing improper activation of the Hog1-type MAPK. However, the appearance of fludioxonil resistant mutants, mostly caused by mutations in the group III histidine kinases, poses a serious problem. Moreover, such

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