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134M-1

Sigma-Aldrich

CD34 (QBEnd/10) Mouse Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Pricing and availability is not currently available.

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

QBEnd/10, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (134M-14)
vial of 0.5 mL concentrate (134M-15)
bottle of 1.0 mL predilute (134M-17)
vial of 1.0 mL concentrate (134M-16)
bottle of 7.0 mL predilute (134M-18)

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BR705732BR705730BR705742
feature

ATP free, barrier: no, includes adapter: no, RNase and DNase free, individually wrapped, endotoxin free

feature

ATP free, RNase and DNase free, barrier: no, endotoxin free, includes adapter: no, individually wrapped

feature

ATP free, RNase and DNase free, barrier: no, endotoxin free, includes adapter: no, individually wrapped

feature

ATP free, RNase and DNase free, barrier: no, endotoxin free, includes adapter: no, individually wrapped

material

high-density polyethylene piston, polypropylene cylinder

material

high-density polyethylene piston, polypropylene cylinder

material

polypropylene cylinder

material

high-density polyethylene piston, polypropylene cylinder

volume

2.5 mL

volume

0.5 mL

volume

0.1 mL

volume

10 mL

General description

CD34 is a cell surface glycophosphoprotein expressed on human hematopoietic progenitor cells and can be used for identifying blast cells.[1] CD34 is a marker for vascular endothelial cells and has been shown in the literature to be highly sensitive to angiosarcomas and Kaposi’s sarcomas. In addition, CD34 is expressed in soft tissue tumors such as gastrointestinal stromal tumors (GIST).[2]

Quality


IVD

IVD

IVD

RUO

Linkage

CD34 Positive Control Slides, Product No. 134S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Joanna Kiśluk et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 22(1), 33-39 (2013-03-08)
Gastrointestinal stromal tumors (GISTs) are the most common cancers of mesenchymal origin in the abdomen. An approximately 95% of GISTs show positive expression of the membrane receptor c-kit (CD117 antigen), which currently constitutes the basis for histopathological diagnosis if this
E A Sankey et al.
The Journal of pathology, 161(3), 267-271 (1990-07-01)
Kaposi's sarcomas are seen more commonly in routine histopathology laboratories since the advent of the more widespread and aggressive variant of the disease associated with HIV infection. Distinguishing nodular lesions from other spindle cell and vascular tumours can sometimes be
P Ramani et al.
Histopathology, 17(3), 237-242 (1990-09-01)
The immunoreactivity of a new monoclonal antibody to endothelium. QBEND/10, in formalin-fixed, paraffin-embedded sections from a variety of vascular and lymphatic tumours is described and compared to that of two other endothelial markers, von Willebrand factor and Ulex europaeus agglutinin
Goran Torlakovic et al.
Archives of pathology & laboratory medicine, 126(7), 823-828 (2002-06-29)
The immunohistochemical detection of CD34 protein using QBEND10 antibody in bone marrow trephine biopsies was shown recently to be a precise method for quantitation of blasts and a possibly useful approach in diagnosis and classification of myelodysplastic syndrome. To evaluate

Articles

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

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