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34861

Sigma-Aldrich

2-Butanone

suitable for HPLC, ≥99.7%

Synonym(s):

Ethyl methyl ketone, MEK, Methyl ethyl ketone

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About This Item

Linear Formula:
C2H5COCH3
CAS Number:
Molecular Weight:
72.11
Beilstein:
741880
EC Number:
MDL number:
UNSPSC Code:
41116105
eCl@ss:
39021202
PubChem Substance ID:
grade:
HPLC grade
technique(s):
HPLC: suitable
application(s):
food and beverages
bp:
80 °C (lit.)
vapor pressure:
71 mmHg ( 20 °C)
Pricing and availability is not currently available.

grade

HPLC grade

vapor density

2.49 (vs air)

vapor pressure

71 mmHg ( 20 °C)

Assay

≥99.7%

form

liquid

autoignition temp.

960 °F

expl. lim.

10.1 %

technique(s)

HPLC: suitable

impurities

≤0.001% free acid (as CH3COOH)
≤0.001% non-volatile matter
≤0.1% water (Karl Fischer)

evapn. residue

≤0.001%

transmittance

335 nm, ≥50%
340 nm, ≥80%
350 nm, ≥98%

refractive index

n20/D 1.379 (lit.)

bp

80 °C (lit.)

mp

−87 °C (lit.)

density

0.805 g/mL at 25 °C (lit.)

λ

neat

UV absorption

λ: 335 nm Amax: ≤0.30
λ: 340 nm Amax: ≤0.10
λ: 350 nm Amax: ≤0.01

application(s)

food and beverages

SMILES string

CC(CC)=O

InChI

1S/C4H8O/c1-3-4(2)5/h3H2,1-2H3

InChI key

ZWEHNKRNPOVVGH-UHFFFAOYSA-N

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General description

Physical properties of the solutions of 1-n-butyl-3-methylimidazolium tetrafluoroborate (ionic liquid) in various organic solvents (acetonitrile, dichloromethane, 2-butanone and N,N-dimethylformamide) has been studied. Viscosity and density of these mixtures were evaluated at 298.15K.[1]

Application

2-Butanone may be employed as a solvent for the methylation agent [11C]methyl trifluoromethanesulfonate ([11C]CH3OTf), during the completely automated radiosynthesis of 2-(4-N-[11C]methylaminophenyl)-6-hydroxybenzothiazole ([11C]PIB).[2]

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Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

30.2 °F - closed cup

Flash Point(C)

-1 °C - closed cup


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A volumetric and viscosity study for the mixtures of 1-n-butyl-3-methylimidazolium tetrafluoroborate ionic liquid with acetonitrile, dichloromethane, 2-butanone and N, N-dimethylformamide.
Wang J, et al.
Green Chemistry, 5(5), 618-622 (2003)
C Philippe et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 69(9), 1212-1217 (2011-05-10)
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L B Goldsmith et al.
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Irritant contact dermatitis along with an increased transepidermal water loss can result from exposing the skin to solvents. A study of the interaction of various solvents with human stratum corneum was made using thin-layer chromatography. Comparison of 10 solvents (trichloroethylene
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Kinase inhibitors block proliferative signals in BCR-ABL1+ leukemic cells, but their capacity to induce apoptosis is poorly understood. Initial studies suggested that very brief exposure to kinase inhibitors was sufficient to induce apoptosis in chronic myeloid leukemia (CML) cells. However

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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