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13767

Supelco

Silica gel orange

with moisture indicator free of heavy metals

Synonym(s):

Silica gel

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About This Item

CAS Number:
112926-00-8
EC Number:
231-545-4
MDL number:
MFCD00011232
UNSPSC Code:
12352309
PubChem Substance ID:
329750331
Pricing and availability is not currently available.

quality

with moisture indicator free of heavy metals

Quality Level

100

impurities

≤0.025% soluble in chloroform

loss

≤2% loss on drying, 150 °C, 3 h

particle size

2-5 mm

capacity

≥25 % absorption capacity (water)

bp

2230 °C

mp

>1600 °C

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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General description

Silica gel orange (Drying pearls Orange) is a commonly employed drying agent.

Application

Silica gel orange (Drying pearls Orange) may be used to provide long-term storage conditions in the following studies:
  • Multiwell plates in a gel drying box during the solid-phase reverse transfection on cell microarrays.[1]
  • Robust protocol for the reverse transfection of cells on small interfering (siRNA) arrays.[2]
It was used to compose the spotting solution of transfection array.[3]

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT1976

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Qingyu Zhang et al.
Brain, behavior, and immunity, 88, 471-481 (2020-04-14)
Increased kynurenine (Kyn) metabolized from tryptophan (Try) is a biomarker in the immune dysfunction of depression. However, the mechanism by which Kyn change promotes depression is poorly defined. Astrocytes are involved in the neuroinflammation of depression. Among the numerous inflammatory
Holger Erfle et al.
Journal of biomolecular screening, 13(7), 575-580 (2008-07-05)
Solid-phase reverse transfection on cell microarrays is a high-throughput method for the parallel transfection of mammalian cells. However, the cells transfected in this way have been restricted so far to microscopy-based analyses. Analysis methods such as reverse transcriptase-polymerase chain reaction
Holger Erfle et al.
Methods in molecular biology (Clifton, N.J.), 785, 277-287 (2011-09-09)
Endocytosis is one of the most essential cellular processes, which enables cells to internalise diverse -material. It is crucial for regulation of receptor activity and signalling, cell polarisation, attachment and motility, and a great number of other cellular functions. A
Miaomiao Jia et al.
The international journal of neuropsychopharmacology, 20(11), 886-895 (2017-10-11)
Leonurine is an active alkaloid that is extracted from Traditional Chinese Medicine Herba leonuri. Emerging evidence indicates that leonurine produces neuroprotective effects in ischemic stroke, Parkinson's disease, and Alzheimer's disease. However, the effect of leonurine in neuropsychiatric disorders, especially in
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Emerging evidence indicates that NLRP3 inflammasome-induced inflammation plays a crucial role in the pathogenesis of depression. Thus, inhibition of NLRP3 inflammasome activation may offer a therapeutic benefit in the treatment of depression. Metformin has been shown to have potential anti-inflammatory
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Questions

1–4 of 4 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Why does the silica gel with product number 13767-500G-R turn black after being used as a desiccant instead of remaining clear as the customer expects?

    1 answer

    1. The orange indicating silica gel initially appears orange or yellow when dry and changes to a dark green color as it absorbs moisture, which may appear close to black. Once saturated, the gel can be regenerated at temperatures of approximately 120°C. It's important not to exceed this temperature as it can damage the color indicator in the gel, making it less effective.

      Helpful?

  4. Silica gel orange (13767): How many times can we regenerate the silica gel in the oven until it's no longer possible?

    1 answer

    1. The number of drying cycles that orange silica gel can be subjected to has not been assessed. The moisture indicating component is an organic compound and will fade after some time, but the moisture absorbing properties should persist.

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