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Y0001432

Minoxidil for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Minoxidil, 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide, 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide

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About This Item

Empirical Formula (Hill Notation):
C9H15N5O
CAS Number:
38304-91-5
Molecular Weight:
209.25
MDL number:
MFCD00063409
UNSPSC Code:
41116107
PubChem Substance ID:
329831424
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

minoxidil

manufacturer/tradename

EDQM

mp

272-274 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NC1=CC(=NC(=N)N1O)N2CCCCC2

InChI

1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2

InChI key

ZIMGGGWCDYVHOY-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Minoxidil for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Activates ATP-activated K+ channels; vasodilator; slow or stop hair loss and promote hair regrowth.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

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Marc R Avram et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 28(10), 894-900 (2002-11-02)
Over the last decade surgical management of hair loss has become an increasingly popular and satisfying procedure for both men and women, as innovations in donor harvesting, graft size, and hairline design have resulted in consistently natural-appearing hair restoration. In
Topical minoxidil for hair loss in women.
D Hong et al.
DICP : the annals of pharmacotherapy, 24(11), 1062-1063 (1990-11-01)
R C Savin et al.
Dermatologic clinics, 11(1), 55-64 (1993-01-01)
The study and common use of minoxidil have legitimized research in common baldness. Prior to this time, with rare exception, the field was dominated by charlatans and "snake oil merchants." Minoxidil has opened the door to scientific inquiry and allowed
[The therapy of androgenetic alopecia with minoxidil].
A Bammel et al.
Deutsche medizinische Wochenschrift (1946), 118(21), 787-789 (1993-05-28)
Susumu Otomo
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 119(3), 167-174 (2002-03-28)
The length and size of hair are depend on the anagen term in its hair cycle. It has been reported that the some cell growth factors, such as VEGF, FGF-5S, IGF-1 and KGF, induce the proliferation of cells in the
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