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D9257

Supelco

Dihydrotachysterol

analytical standard

Synonym(s):

9,10-Secoergosta-5,7,22-trien-3β-ol, DHT2

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About This Item

Empirical Formula (Hill Notation):
C28H46O
CAS Number:
67-96-9
Molecular Weight:
398.66
EC Number:
200-672-7
UNSPSC Code:
41116107
PubChem Substance ID:
24894275
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98%

form

solid

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]([C@@]1([H])CC[C@@]2([H])/C(CCC[C@@]21C)=C/C=C3[C@@H](C)CC[C@H](O)C/3)/C=C/[C@H](C)C(C)C

InChI

1S/C28H46O/c1-19(2)20(3)12-13-22(5)25-16-17-26-23(10-8-18-28(25,26)6)14-15-24-21(4)9-7-11-27(24)29/h12-15,19-22,25-27,29H,7-11,16-18H2,1-6H3/b13-12+,23-14+,24-15+/t20-,21-,22+,25?,26?,27-,28+/m0/s1

InChI key

DTSXXSAWQHPLEF-GFVAUXBKSA-N

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General description

Dihydrotachysterol is a vitamin D analog in the reduced form, which has implications in the studies of calcemic and cell differentiating action of the hormone, 1α,25-dihydroxyvitamin D3. It has been indicated as a medication for the treatment of hypoparathyroidism and renal osteodystrophy.

Application

Dihydrotachysterol may be used as an analytical reference standard for the determination of the analyte in biological samples by chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H413

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF3829V
WXBF3530V
WXBD8184V
WXBD4543V
WXBC9660V

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Ali Mohammad Tohari et al.
Experimental cell research, 392(1), 112023-112023 (2020-04-24)
Diabetic retinopathy (DR) is a diabetes-associated complication characterized by irreversible deterioration of the microvessels within the retina, leading subsequently to severe retinal damage and vision loss. Vitamin D (VITD), a steroid hormone, plays multiple physiological functions in cellular homeostasis. Deficiency
Gas chromatographic studies of vitamins D2 and D3
Nair PP, et al.
Analytical Chemistry, 37(6), 631-636 (1965)
Serum dihydrotachysterol levels and biological action in normal man
TAYLOR A, et al.
The Journal of clinical endocrinology and metabolism, 67(1), 198-202 (1988)
P Schneider et al.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 112(8), 444-450 (2004-09-17)
This observational study analyzes Ca-P metabolism and its impact on bone mass accrual and density and the muscle-bone mass/mass relationships in male and female children and adolescents who were parathyroidectomized because of thyroid carcinoma. Two hundred and eight children and
D R Jehle et al.
Journal of medicine, 30(1-2), 39-50 (1999-10-09)
During vitamin-D therapy drug accumulation and intoxication should be considered. In the present study we report on five patients with renal insufficiency during therapy with dihydrotachysterol or calcitriol. Four patients received dihydrotachysterol for 29 (7-44) years and one patient received
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