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Key Documents

C1915

Supelco

Chloropyramine hydrochloride

analytical standard, for drug analysis

Synonym(s):

N-p-Chlorobenzyl-N′,N′-dimethyl-N-(2-pyridyl)ethylenediamine

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About This Item

Empirical Formula (Hill Notation):
C16H20ClN3 · HCl
CAS Number:
Molecular Weight:
326.26
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.CN(C)CCN(Cc1ccc(Cl)cc1)c2ccccn2

InChI

1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H,11-13H2,1-2H3;1H

InChI key

VEYWWAGBHABATA-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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[Application of aqueous Eudragit dispersions to the preparation of controlled release oral antihistamine dosage forms].
A Dévay et al.
Acta pharmaceutica Hungarica, 58(4), 166-172 (1988-07-01)
M Budihna et al.
Pflugers Archiv : European journal of physiology, 431(6 Suppl 2), R217-R218 (1996-01-01)
In isolated rat hearts effects of chloropyramine (CP), histamine H1 antagonist, and famotidine (FA), H2 antagonist, upon two different myocardial injuries, ischaemia-reperfusion and hypoxia-reoxygenation were studied. In both types of injury the effects of drugs were seen mainly during reperfusion
[Toxico-allergic form of erythema multiforme exudativum caused by suprastin].
S M Fedorov et al.
Vestnik dermatologii i venerologii, (9)(9), 50-51 (1986-01-01)
D B Beleslin et al.
Neuropharmacology, 26(8), 1157-1165 (1987-08-01)
The emetic action of noradrenaline was investigated in unanesthetized cats, after it was injected into the cerebral ventricles through chronically implanted cannulae. Intracerebroventricular injection of noradrenaline produced dose-dependent and shortlasting emesis, which was abolished after ablation of the area postrema.
S Sipka et al.
International archives of allergy and immunology, 97(1), 89-92 (1992-01-01)
Using human platelet-rich plasma (PRP) we found that histamine concentration-dependently potentiated platelet aggregation induced by platelet-activating factor (PAF). When added separately, neither histamine nor chloropyramine, a competitive antagonist of H1 receptors, influenced platelet aggregation, however BN 52021, a specific PAF

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