61739

N-Lauroylsarcosine

purum p.a., ≥98.0% (GC)

• Synonym(s): N-Dodecanoyl-N-methylglycine, Sarkosyl L
• Linear Formula: CH₃(CH₂)₁₀CON(CH₃)CH₂COOH
• CAS Number: 97-78-9
• Molecular Weight: 271.40
• Beilstein: 1792084
• EC Number: 202-608-3
• MDL number: MFCD00021749
• UNSPSC Code: 12352100
• PubChem Substance ID: 57651861
• NACRES: NA.21

Properties

• description: anionic
• Quality Level: 200
• grade: purum p.a.
• Assay: ≥98.0% (GC)
• mol wt: 271.40 g/mol
• technique(s): protein quantification: suitable
• impurities: ≤0.2% water
• ign. residue: ≤0.1%
• mp: 45-50 °C
• anion traces: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• cation traces: Ca: ≤20 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; K: ≤70 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤200 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤20 mg/kg
• functional group: amide; carboxylic acid
• SMILES string: CCCCCCCCCCCC(=O)N(C)CC(O)=O
• InChI: 1S/C15H29NO3/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19/h3-13H2,1-2H3,(H,18,19)
• InChI key: BACYUWVYYTXETD-UHFFFAOYSA-N

Description

General description

N-Lauroylsarcosine (N-Dodecanoyl-N-methylglycine, Sarkosyl L, LS) is an anionic surfactant. Its microbicidal action against herpes simplex type 2 (HSV-2) intravaginal infection in a murine model has been investigated.

Application

N-Lauroylsarcosine may be used as a permeation enhancer in the transdermal drug delivery formulations since it increases the fluidity of stratum corneum lipid structure of the skin†

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H315,H318,H330
• Precautionary Statements: P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves