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447293

Sigma-Aldrich

5(6)-Carboxyfluorescein

Dye content 90 %

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About This Item

Empirical Formula (Hill Notation):
C21H12O7
CAS Number:
72088-94-9
Molecular Weight:
376.32
EC Number:
276-331-1
MDL number:
MFCD00151081
UNSPSC Code:
12171500
PubChem Substance ID:
329756539
NACRES:
NA.47

Assay

≥89.5% (HPLC)

Quality Level

100

form

powder

composition

Dye content, 90%

mp

275 °C (dec.) (lit.)

λmax

492 nm

ε (extinction coefficient)

12134 at 284 nm in 0.1 M NaOH at 0.005 g/L
43060 at 239 nm in 0.1 M NaOH at 0.005 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

OC(=O)c1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35.OC(=O)c6ccc7C(=O)OC8(c9ccc(O)cc9Oc%10cc(O)ccc8%10)c7c6

InChI

1S/2C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21;22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h2*1-9,22-23H,(H,24,25)

InChI key

BPVHBBXCESDRKW-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCK7036
MKCJ8194
MKCG6805
MKCD3055
MKBX5657V

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Jorien Claes et al.
Blood, 124(10), 1669-1676 (2014-06-22)
Adhesion of Staphylococcus aureus to blood vessels under shear stress requires von Willebrand factor (VWF). Several bacterial factors have been proposed to interact with VWF, including VWF-binding protein (vWbp), a secreted coagulase that activates the host's prothrombin to generate fibrin.
Zhiqiang Cao et al.
Langmuir : the ACS journal of surfaces and colloids, 28(31), 11625-11632 (2012-07-13)
Nonionic polyethylene glycol (PEG) as a stealth polymer destabilizes liposomes due to its amphiphilic property. As a result, PEGylated liposomes have to be further stabilized, such as by using a large amount cholesterol. This is a long existing dilemma faced
Wensheng Chen et al.
PloS one, 7(7), e40893-e40893 (2012-07-21)
Preservatives are a major component of the ophthalmic preparations in multi-dose bottles. The purpose of this study was to investigate the acute effect of benzalkonium chloride (BAC), a common preservative used in ophthalmic preparations, on the localization and expression of
Suguru Nakagawa et al.
Investigative ophthalmology & visual science, 53(9), 5154-5160 (2012-06-15)
To investigate the toxicity profiles of seven antiglaucoma topical eye drops and benzalkonium chloride (BAC) using stratified cultivated human corneal epithelial cell sheets (HCES) in a serum-free culture system. A range of prostaglandin analogies and preservatives, including BAC, sofZia (SZ)
Martin Hossann et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 400-406 (2012-07-05)
Thermosensitive liposomes (TSL) are a promising tool for triggered drug delivery in combination with local hyperthermia. Objective of this study was to investigate the influence of serum on TSL in more detail and to identify serum components which are responsible
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