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34092

Supelco

Resveratrol

analytical standard

Synonym(s):

3,4′,5-Trihydroxy-trans-stilbene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol

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About This Item

Empirical Formula (Hill Notation):
C14H12O3
CAS Number:
Molecular Weight:
228.24
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

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grade

analytical standard

Quality Level

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

InChI key

LUKBXSAWLPMMSZ-OWOJBTEDSA-N

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General description

Resveratrol, a non-flavonoid polyphenolic compound, is widely found in the skin of red grapes, nuts, berries, Polygonum cuspidatum root, etc. It is reportedly known to exhibit pharmacological properties including anti-cancer, anti-inflammatory, antioxidant, neuroprotectant, anti-atherogenic property and reduces the synthesis of pro-atherosclerotic substances.[1][2]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Resveratrol has been used as a phenolic analytical standard to determine its content in oat flour tarhana[3] and different varieties of chicory[4] using high-performance liquid chromatography with diode array detection (HPLC-DAD). It has also been used as an analytical standard to investigate its effectiveness in modulating several signaling pathways that are involved in carcinogenesis, via determining its anti-tumor potential in colorectal cancer as a proapoptotic agent in colorectal cancer cell lines, including HCT116, CO115 and SW48.[1]
Selective inhibitor of COX−1.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

>392.0 °F - closed cup - (External MSDS)

Flash Point(C)

> 200.0 °C - closed cup - (External MSDS)

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    The impact of drying techniques on phenolic compound, total phenolic content and antioxidant capacity of oat flour tarhana
    Degirmencioglu N, et al.
    Food Chemistry, 194, 587-594 (2016)
    Resveratrol induces p53 in colorectal cancer through SET7/9
    Liu Z, et al.
    Oncology Letters, 17(4), 3783-3789 (2019)
    Biological effects of resveratrol
    Fremont L
    Life Sciences, 66, 663-673 (2000)
    Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
    Lu R and Serrero G
    Journal of Cellular Physiology, 179, 297-304 (1999)
    HPLC?tandem mass spectrometric method to characterize resveratrol metabolism in humans
    Urpi-Sarda M, et al.
    Clinical Chemistry, 53(2), 292-299 (2007)

    Articles

    Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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