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33746

Supelco

Moxidectin

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C37H53NO8
CAS Number:
Molecular Weight:
639.82
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

−20°C

SMILES string

CO\N=C1/C[C@]2(C[C@@H]3CC(C\C=C(C)\C[C@@H](C)\C=C\C=C4/COC5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)O[C@@H]([C@H]1C)\C(C)=C\C(C)C

InChI

1S/C37H53NO8/c1-21(2)14-25(6)33-26(7)31(38-42-8)19-36(46-33)18-29-17-28(45-36)13-12-23(4)15-22(3)10-9-11-27-20-43-34-32(39)24(5)16-30(35(40)44-29)37(27,34)41/h9-12,14,16,21-22,26,28-30,32-34,39,41H,13,15,17-20H2,1-8H3/b10-9+,23-12+,25-14+,27-11+,38-31+/t22-,26-,28+,29-,30-,32+,33+,34+,36-,37+/m0/s1

InChI key

YZBLFMPOMVTDJY-LSGXYNIPSA-N

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General description

Chemical structure: ß-lactam
Moxidectin is a semisynthetic milbemycin derivative of nemadectin, which is used as an anthelmintic drug.

Application

Moxidectin may be used as a reference standard in the determination of moxidectin residues in liver samples using high-performance liquid chromatography coupled with a fluorescence detector (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Kirk's Current Veterinary Therapy XIV (2013)
Sheep Flock Health: A Planned Approach (2009)
Multiresidue method for the determination of avermectin and moxidectin residues in the liver using HPLC with fluorescence detection.
Roudaut B.
Analyst, 123(12), 2541-2544 (1998)
Multiple anthelmintic resistance of Haemonchus contortus, including a case of moxidectin resistance, in a Dutch sheep flock.
R Van den Brom et al.
The Veterinary record, 173(22), 552-552 (2013-11-08)
Esra Yilmaz et al.
Experimental parasitology, 200, 61-66 (2019-04-05)
Anthelmintic and in particular macrocyclic lactone (ML) resistance is a widespread problem in trichostrongyloid parasitic nematodes, yet mechanisms of ML resistance are still poorly understood. In the absence of target-site changes in resistant parasite field populations, increased drug extrusion and

Protocols

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Test your food for fipronil contamination using our analytical standards, certified reference materials, solvents, and columns for analysis.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service