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Key Documents

324558

Sigma-Aldrich

Ethylene glycol

anhydrous, 99.8%

Synonym(s):

1,2-Ethanediol

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About This Item

Linear Formula:
HOCH2CH2OH
CAS Number:
Molecular Weight:
62.07
Beilstein:
505945
EC Number:
MDL number:
UNSPSC Code:
12191502
eCl@ss:
39020501
PubChem Substance ID:
NACRES:
NA.21

grade

anhydrous

Quality Level

vapor density

2.1 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

Assay

99.8%

form

liquid

autoignition temp.

752 °F

expl. lim.

15.3 %

impurities

<0.003% water
<0.005% water (100 mL pkg)

refractive index

n20/D 1.431 (lit.)

bp

195-198 °C

mp

−13 °C (lit.)

density

1.113 g/mL at 25 °C (lit.)

SMILES string

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Ethylene glycol is the major component of antifreeze preparations.

Application

Ethylene glycol may be used in the preparation of spiroborate esters by reacting with chiral 1,2-aminoalcohols in the presence of triisopropyl borate. It may also be used as a solvent in the preparation of tris(2,2′-bipyrazyl)ruthenium(II) chloride by the reaction of 2,2′-bipyrazine with ruthenium(III) chloride.

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

Target Organs

Kidney

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

239.0 °F - open cup

Flash Point(C)

115 °C - open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis of spiroborate esters from 1,2-aminoalcohols, ethylene glycol and triisopropyl borate: preparation of (S)-1-(1,3,2-dioxaborolan-2-yloxy)-3-methyl-1,1-diphenylbutan-2-amine
Stepanenko V, et al.
Organic Syntheses, 87, 26-26 (2010)
Bis(tetrakis(3,5-bis(trifluoromethyl)phenyl)borate)
Lies SD, et al.
Organic Syntheses, 93, 178-178 (2016)
The spectrum of ethylene glycol poisoning.
Moriarty RW & McDonald RH.
Clinical Toxicology, 7(6), 583-596 (1974)
Gregory Charles Nordmann et al.
Scientific reports, 10(1), 915-915 (2020-01-24)
The transcription factor ZENK is an immediate early gene that has been employed as a surrogate marker to map neuronal activity in the brain. It has been used in a wide variety of species, however, commercially available antibodies have limited
Peter Mygind Leth et al.
Forensic science international, 155(2-3), 179-184 (2005-10-18)
Ethylene glycol (EG) can be found in many agents, such as antifreeze. Ingestion of EG may cause serious poisoning. Adults are typically exposed when EG is ingested as a cheap substitute for ethanol or in suicide-attempts. Children may be exposed

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