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MAB5782

Sigma-Aldrich

Anti-NMDAR2B Antibody, NT

ascites fluid, clone 1A8.9B3, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

clone

1A8.9B3, monoclonal

species reactivity

human, rabbit, fish, rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000834.2

UniProt accession no.

Q13224

shipped in

dry ice

target post-translational modification

unmodified

Specificity

NMDAR2B, N-terminal. By Western blot the antibody reacts with bands at ~170 kDa on rat brain lysate. Additional bands at ~116, 50 and 32 kDa may be seen depending on sample and antibody concentration used.

Application

Detect NMDAR2B using this Anti-NMDAR2B Antibody, N-terminal validated for use in WB.
Western blot: 1:100-1:1,000 on rat brain lysate.

Optimal working dilutions must be determined by end user.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Andry Andrianarivelo et al.
Science advances, 7(43), eabg5970-eabg5970 (2021-10-21)
[Figure: see text].
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Fear-related disorders, including post-traumatic stress disorder (PTSD), and anxiety disorders are pervasive psychiatric conditions marked by persistent fear, stemming from its dysregulated acquisition and extinction. The primary treatment for these disorders, exposure therapy (ET), relies heavily on fear extinction (FE)
D J Laurie et al.
Brain research. Molecular brain research, 51(1-2), 23-32 (1998-01-14)
Mouse monoclonal antibodies were raised against bacterially expressed protein sequences of the NR2A, NR2B, NR2C and NR2D subunits of the rat NMDA receptor. From immunoblots of rat brain proteins, the apparent molecular weights of these subunits were 165, 170, 135
Verónica Guirao et al.
Journal of neurochemistry, 143(3), 359-374 (2017-09-08)
The statin atorvastatin (ATV) given as a post-treatment has been reported beneficial in stroke, although the mechanisms involved are not well understood so far. Here, we investigated in vitro the effect of post-treatment with ATV and its main bioactive metabolite ortho-hydroxy
Núria DeGregorio-Rocasolano et al.
Antioxidants (Basel, Switzerland), 9(12) (2020-12-04)
Death-associated protein kinase 1 (DAPK1) is a pleiotropic hub of a number of networked distributed intracellular processes. Among them, DAPK1 is known to interact with the excitotoxicity driver NMDA receptor (NMDAR), and in sudden pathophysiological conditions of the brain, e.g.

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