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Key Documents

MAB3658

Sigma-Aldrich

Anti-TATA-Binding-Protein Antibody

ascites fluid, Chemicon®

Synonym(s):

TBP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

monoclonal

species reactivity

mouse, human, zebrafish, Xenopus, chicken, fish

should not react with

Drosophila

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TBP(6908)

Specificity

Reactivity with other species has not been confirmed.
Recognizes TATA-binding-protein (TBP). Recognizes an epitope from the first 18 amino acids of human TBP.

Immunogen

Epitope: a.a. 1-18
Full length recombinant human TBP.

Application

Anti-TATA-Binding-Protein Antibody is a Mouse Monoclonal Antibody for detection of TATA-Binding-Protein also known as TBP & has been validated in WB, ICC & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Western blot: 1:1,000-1:5,000 on endogenous and recombinant protein.

Immunohistochemistry: 1:1,000-1:5,000

Immunocytochemistry: 1:1,000-1:5,000

Immunoprecipitation

ELISA: 1:1,000-1:5,000

Optimal working dilutions must be determined by the end user.

Target description

~42 kDa

Physical form

Ascites. Liquid. Contains no preservative.
Unpurified

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xinan Holly Yang et al.
Scientific reports, 7(1), 41-41 (2017-03-02)
c-Myc dysregulation is hypothesized to account for the 'stemness' - self-renewal and pluripotency - shared between embryonic stem cells (ESCs) and adult aggressive tumours. High-risk neuroblastoma (HR-NB) is the most frequent, aggressive, extracranial solid tumour in childhood. Using HR-NB as
José R Naranjo et al.
The Journal of clinical investigation, 126(2), 627-638 (2016-01-12)
Deregulated protein and Ca2+ homeostasis underlie synaptic dysfunction and neurodegeneration in Huntington disease (HD); however, the factors that disrupt homeostasis are not fully understood. Here, we determined that expression of downstream regulatory element antagonist modulator (DREAM), a multifunctional Ca2+-binding protein
Moses New-Aaron et al.
Biomolecules, 11(10) (2021-10-24)
Although the causes of hepatotoxicity among alcohol-abusing HIV patients are multifactorial, alcohol remains the least explored "second hit" for HIV-related hepatotoxicity. Here, we investigated whether metabolically derived acetaldehyde impairs lysosomes to enhance HIV-induced hepatotoxicity. We exposed Cytochrome P450 2E1 (CYP2E1)-expressing
A Raquel Esteves et al.
Redox biology, 63, 102714-102714 (2023-05-01)
Sporadic Parkinson's disease (sPD) is a complex multifactorial disorder which etiology remains elusive. Several mechanisms have been described to contribute to PD development namely mitochondrial dysfunction, activation of inflammatory pathways and the deposition of unfolded proteins such as α-synuclein. Our
Linyan Meng et al.
PLoS genetics, 9(12), e1004039-e1004039 (2014-01-05)
Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by maternal deficiency of the imprinted gene UBE3A. Individuals with AS suffer from intellectual disability, speech impairment, and motor dysfunction. Currently there is no cure for the disease. Here, we evaluated

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