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E-076

Supelco

17α-Ethynylestradiol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C20H24O2
CAS Number:
57-63-6
Molecular Weight:
296.40
MDL number:
MFCD01004605
UNSPSC Code:
41116107
PubChem Substance ID:
329798988
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

OC1=CC=C2C3([H])CCC4(C)C(O)(C#C)CCC4([H])C3([H])CCC2=C1

InChI

1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3

InChI key

BFPYWIDHMRZLRN-UHFFFAOYSA-N

General description

A new Certified Spiking Solution® and certified solution standard suitable for LC/MS and GC/MS applications from clinical and diagnostic testing, endocrinology, and clinical chemistry to environmental testing for EPA Method 1698. 17α-Ethynylestradiol is one of the most commonly used medications and can be found in almost all modern formulations of combined oral contraceptive pills.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 1 - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A Frølich et al.
Bone, 11(6), 393-396 (1990-01-01)
An attempt was made to explain the bone-preserving effect of estrogen by analysis of estrogen receptors (OER) in the calcitonin-producing C-cells of the human thyroid gland. Thyroid tissue from twenty patients with benign hyperthyroidism and three patients with medullary thyroid
Rachid Safi et al.
Cancer research, 65(24), 11762-11770 (2005-12-17)
Aromatase inhibitors target the production of estrogen in breast adipose tissue, but in doing so, also decrease estrogen formation in bone and other sites, giving rise to deleterious side effects, such as bone loss and arthralgia. Thus, it would be
Ahmed M Al-Ansari et al.
Aquatic toxicology (Amsterdam, Netherlands), 132-133, 134-140 (2013-03-19)
We used male goldfish (Carassius auratus) as a model species to determine the uptake, elimination, and bioaccumulation of 17α-ethinylestradiol (EE2). Goldfish were exposed to EE2 via two different routes: water (135ng/L±12.8 standard deviation) for 72h, and food (231ng/g±42 SD) for
Bernardine H Stegeman et al.
BMJ (Clinical research ed.), 347, f5298-f5298 (2013-09-14)
To provide a comprehensive overview of the risk of venous thrombosis in women using different combined oral contraceptives. Systematic review and network meta-analysis. PubMed, Embase, Web of Science, Cochrane, Cumulative Index to Nursing and Allied Health Literature, Academic Search Premier
Willi Cawello et al.
Epilepsia, 54(3), 530-536 (2013-01-31)
To determine whether the antiepileptic drug lacosamide affects the pharmacokinetics or pharmacodynamics of a combined oral contraceptive (OC; ethinylestradiol 0.03 mg plus levonorgestrel 0.15 mg). This was an open-label trial in healthy female volunteers. Eligible women entered cycle 1 of the trial
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