The solubility in DMSO is not tested internally, but literature indicates that it may be soluble up to 50 mg/mL. Solution stability is not tested, so it would be best to prepare a fresh solution as needed. There is no internal information regarding half life.
N5893
(±)-Naringenin
≥95%
Synonym(s):
(±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4′,5,7-Trihydroxyflavanone
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About This Item
Empirical Formula (Hill Notation):
C15H12O5
CAS Number:
Molecular Weight:
272.25
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.
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Quality Level
Assay
≥95%
form
powder
mp
247-250 °C (lit.)
SMILES string
OC1=CC=C(C=C1)C(C2)OC3=CC(O)=CC(O)=C3C2=O
InChI
1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
InChI key
FTVWIRXFELQLPI-UHFFFAOYSA-N
Gene Information
human ... CYP1A2(1544)
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Application
(±)-Naringenin, a polyphenolic material, is used to prepare nickel(II) naringenin-oxime complex, which can be used as a catalyst for Mizoroki−Heck cross-coupling reaction.[1] It has been used as a hypochlorite scavenger to prevent the formation of chloramines from oxidation of hypochlorite in the human serum albumin.[2] It induces apoptosis in human pancreatic cancer SNU-213 cells.[3] It also shows cytotoxic effects on various human cancer cells such as breast, cervix, stomach, colon and liver cancer cells.[4]
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Articles
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
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I need to know what is the solubility of naringenin in DMSO before buying? And what is the half life and stability? Can I store the solution or I should to prepare it daily?
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