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Key Documents

G6104

Sigma-Aldrich

Glycinamide hydrochloride

98%

Synonym(s):

2-Aminoacetamide hydrochloride, Aminoacetamide hydrochloride, Glycine amide hydrochloride

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About This Item

Linear Formula:
NH2CH2CONH2 · HCl
CAS Number:
Molecular Weight:
110.54
Beilstein:
3554199
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

mp

204 °C (dec.) (lit.)

SMILES string

Cl.NCC(N)=O

InChI

1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H

InChI key

WKNMKGVLOWGGOU-UHFFFAOYSA-N

Application

Buffer useful in the physiological pH range.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Irene M Lagoja et al.
Chemistry & biodiversity, 2(7), 923-927 (2006-12-29)
A possible reaction mechanism for the dehydration of glycinamide (3) and N,N'-diformylurea (4) yielding hypoxanthine (2) has been investigated. Furthermore, a potential prebiotic route converting hypoxanthine (2) into adenine (1) via phosphate activation followed by substitution reaction with NH3 was
Yong Sun et al.
The journal of physical chemistry. B, 109(12), 5919-5926 (2006-07-21)
For the purpose of investigating the tautomerism from glycinamide (G) to glycinamidic acid (G*) induced by proton transfer, we carried out a study of structural interconversion of the two tautomers and the relative stabilizing influences of water during the tautomerization
Irene M Lagoja et al.
Chemistry & biodiversity, 1(1), 106-111 (2006-12-29)
Because of their easy availability and their relative chemical stability, urea, formic acid, and glycine might have played a role in the assembly process of nucleobases. In this paper, a short reaction path is described to prepare hypoxanthine starting from
Ajeet Singh et al.
Langmuir : the ACS journal of surfaces and colloids, 23(10), 5406-5411 (2007-04-14)
Conformational behaviors of urea and glycinamide have been investigated using the B3LYP functional with the 6-311+G* and 6-311+G** basis sets. Urea monomers have nonplanar minima at all the levels studied, even in the aqueous phase. In the case of glycinamide
Len Ito et al.
FEBS letters, 585(3), 555-560 (2011-01-18)
Glycine amide (GlyAd), a typically amidated amino acid, is a versatile additive that suppresses protein aggregation during refolding, heat treatment, and crystallization. In spite of its effectiveness, the exact mechanism by which GlyAd suppresses protein aggregation remains to be elucidated.

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