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D141003

Sigma-Aldrich

2-(Dimethylamino)ethanethiol hydrochloride

95%

Synonym(s):

MEDA

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About This Item

Linear Formula:
(CH3)2NCH2CH2SH · HCl
CAS Number:
Molecular Weight:
141.66
Beilstein:
3906670
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

form

solid

mp

150-160 °C (lit.)

SMILES string

Cl.CN(C)CCS

InChI

1S/C4H11NS.ClH/c1-5(2)3-4-6;/h6H,3-4H2,1-2H3;1H

InChI key

NRVFDGZJTPCULU-UHFFFAOYSA-N

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Application

2-(Dimethylamino)ethanethiol hydrochloride can be used:
  • To synthesize fluorescent thiocholine esters containing dansyl group in the acyl portions, which are potent substrates for the human fibrinoligase.
  • As a cationic ligand for the surface modification of gold nanoparticles.
  • For the modification of cellulose 10-undecenoyl ester (CUE) to form organo-soluble ionic cellulose derivatives.

Metal-complexing agent

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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New thioester substrates for fibrinoligase (coagulation factor XIIIa) and for transglutaminase. Transfer of the fluorescently labeled acyl group to amines and alcohols
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A Valero et al.
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