Poly(oligo(ethylene glycol) methacrylate) (POEGMA) 300 is a family of polymers consisting of a hydrophobic methacrylate backbone and hydrophilic ethylene oxide (EO) side groups with highly branched architecture. The highly branched architecture with a high density of oligo EO moieties enhances the solubility of the polymer in water.
Application
Drug delivery- enhances the stability and delivery of siRNA and eliminates PEG antigenicity
Biosensor coatings- provides an anti-fouling surface
Stimuli-responsive hydrogels for tissue engineering, drug delivery, and other biomedical applications
Features and Benefits
Highly branched architecture and high density of oligo ethylene oxide moieties
Water soluble
Nonfouling and thermo-responsive behaviors
Viable alternative to PEG in biological and biomaterial applications
Lower critical solution temperature (LCST) behavior
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