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923753

Sigma-Aldrich

INVIVO-GEL TGF-β bioink

suitable for 3D bioprinting applications

Synonym(s):

3D bioprinting, 3DBP, ECM

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

Pricing and availability is not currently available.

Quality Level

storage temp.

2-8°C

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This Item
923745923796915637
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

Application

INVIVO-GEL TGF-β bioink is specifically developed and optimized for 3D bioprinting applications. The INVIVO-GEL TGF-β bioink kit includes optimally formulated TGF-mimetic peptide conjugated gelatin-based hydrogel complex packed in syringe for easy dispensing. The kit also includes Gel-linker, which reinforces mechanical stability. A transparent hydrogel forms when contents are properly mixed and exposed to UV light. This bioink is capable of generating mechanically stable 3D structures that can be maintained for days in the culture environment. TGF may promote ECM production, as reported by numerous studies demonstrating the dramatic increase in matrix synthesis and deposition by vascular smooth muscle and endothelial cells when grown on hydrogels with tethered TGF-β.

Components

INVIVO-GEL TGF-β in syringe 5mL x 2
Gel-linker(A) powder 500µL x 1
Gel-linker(B) powder 1µL x 1

Pictograms

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Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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    Designing Gelatin Methacryloyl (GelMA)-Based Bioinks for Visible Light Stereolithographic 3D Biofabrication
    Kumar H et al.
    Macromolecular Bioscience, 11 (2020)
    Gelatin methacryloyl and its hydrogels with an exceptional degree of controllability and batch-to-batch consistency
    Zhu et al.
    Scientific Reports, 9, 6863-6863 (2019)
    Synergetic roles of TGF-? signaling in tissue engineering
    Lee et al.
    Cytokine, 115, 60?63-60?63 (2019)
    Shining Xiao et al.
    Stem cell reviews and reports, 15(5), 664-679 (2019-06-04)
    Gelatin methacrylate (GelMA)-based hydrogels are gaining a great deal of attention as potentially implantable materials in tissue engineering applications because of their biofunctionality and mechanical tenability. Since different natural tissues respond differently to mechanical stresses, an ideal implanted material would
    Kan Yue et al.
    Biomaterials, 73, 254-271 (2015-09-29)
    Gelatin methacryloyl (GelMA) hydrogels have been widely used for various biomedical applications due to their suitable biological properties and tunable physical characteristics. GelMA hydrogels closely resemble some essential properties of native extracellular matrix (ECM) due to the presence of cell-attaching

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