Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

540935

Sigma-Aldrich

4-(N-Boc-amino)piperidine

96%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H20N2O2
CAS Number:
73874-95-0
Molecular Weight:
200.28
MDL number:
MFCD00798171
UNSPSC Code:
12352100
PubChem Substance ID:
24878503
NACRES:
NA.22

Assay

96%

mp

162-166 °C (lit.)

functional group

amine

SMILES string

CC(C)(C)OC(=O)NC1CCNCC1

InChI

1S/C10H20N2O2/c1-10(2,3)14-9(13)12-8-4-6-11-7-5-8/h8,11H,4-7H2,1-3H3,(H,12,13)

InChI key

CKXZPVPIDOJLLM-UHFFFAOYSA-N

General description

4-(N-Boc-amino)piperidone is a piperidone derivative.

Application

4-(N-Boc-amino)piperidone may be used as a functionalization reagent for introduction of a primary and a tertiary amino group to poly(2-isopropyl-2-oxazoline.
Pharma building block.
Used in a synthesis of a piperidine-4-carboxamide CCR5 antagonist with potent anti-HIV-1 activity.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCS2982
MKCL7713
MKCN7217
MKCM3337
MKBW4312V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Poly (2-isopropyl-2-oxazoline)-poly (L-glutamate) block copolymers through ammonium-mediated NCA polymerization.
Meyer M and Schlaad H.
Macromolecules, 39(11), 3967-3970 (2006)
Apos Dermatakis et al.
Bioorganic & medicinal chemistry, 11(8), 1873-1881 (2003-03-28)
A series of oxindole CDK2 inhibitors was synthesized. These novel analogues have a saturated monosubstituted cyclic moiety at their C-4 position that mimics the ribofuranoside of ATP. This substitution afforded agents with increased potency relative to the parent indolinone and
Shinichi Imamura et al.
Journal of medicinal chemistry, 49(9), 2784-2793 (2006-04-28)
We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group into the phenyl ring of the 4-benzylpiperidine moiety afforded the less lipophilic compound 5f, which possessed

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service