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Key Documents

445177

Sigma-Aldrich

O,O-Diethyl thiophosphate potassium salt

98%

Synonym(s):

Potassium O,O-diethyl phosphorothioate, Potassium O,O-diethylthiophosphate, Potassium di-O-ethyl phosphorothioate, Potassium diethyl thiophosphate

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About This Item

Linear Formula:
(C2H5O)2P(O)SK
CAS Number:
Molecular Weight:
208.26
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

solid

mp

180-186 °C (lit.)

SMILES string

[K+].CCOP([O-])(=S)OCC

InChI

1S/C4H11O3PS.K/c1-3-6-8(5,9)7-4-2;/h3-4H2,1-2H3,(H,5,9);/q;+1/p-1

InChI key

OVJCAYMARFNMQB-UHFFFAOYSA-M

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Jialong Jie et al.
Nucleic acids research, 47(22), 11514-11526 (2019-11-15)
Phosphorothioate (PS) modifications naturally appear in bacteria and archaea genome and are widely used as antisense strategy in gene therapy. But the chemical effects of PS introduction as a redox active site into DNA (S-DNA) is still poorly understood. Herein
Personnel exposure to diazinon in a supervised pest eradication program.
C P Weisskopf et al.
Archives of environmental contamination and toxicology, 17(2), 201-212 (1988-03-01)
M E Mount
American journal of veterinary research, 45(4), 817-824 (1984-04-01)
Recognition of exposure to diazinon, an organophosphate insecticide, was studied in goats. Urine and milk dialkyl phosphate concentrations (DETP; O,O-diethyl phosphorothionate) and blood cholinesterase activity (ChE) and diazinon concentrations were measured. Groups (n = 3 each) given (orally) diazinon at
L C Sánchez-Peña et al.
Toxicology and applied pharmacology, 196(1), 108-113 (2004-03-31)
Our objective was to evaluate alterations in sperm chromatin structure in men occupationally exposed to a mixture of organophosphorus pesticides (OP) because these alterations have been proposed to compromise male fertility and offspring development. Chromatin susceptibility to in situ acid-induced
V Drevenkar et al.
Chemico-biological interactions, 87(1-3), 315-322 (1993-06-01)
Concentrations of parent pesticide and corresponding diethylphosphorus metabolites in blood serum and urine were investigated in persons who had ingested a concentrated solution of organophosphorus pesticide chlorpyrifos. The organophosphate poisoning was indicated by a significant depression of blood cholinesterase (EC

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