Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

263389

Sigma-Aldrich

3,5-Bis(trifluoromethyl)benzylamine

technical grade, 80%

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
(CF3)2C6H3CH2NH2
CAS Number:
85068-29-7
Molecular Weight:
243.15
Beilstein:
7209267
EC Number:
285-290-9
MDL number:
MFCD00009909
UNSPSC Code:
12352100
PubChem Substance ID:
24855967
NACRES:
NA.22

grade

technical grade

Assay

80%

form

solid

mp

50-55 °C (lit.)

functional group

amine

SMILES string

NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI

1S/C9H7F6N/c10-8(11,12)6-1-5(4-16)2-7(3-6)9(13,14)15/h1-3H,4,16H2

InChI key

DHVHORCFFOSRBP-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

3,5-Bis(trifluoromethyl)benzylamine has been used in the preparation of phenyl glycine derivatives.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

172.4 °F - closed cup

Flash Point(C)

78 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lihu Yang et al.
Bioorganic & medicinal chemistry letters, 16(14), 3735-3739 (2006-05-16)
Systematic modification of a screening lead yielded a class of potent glycinamide based CCR2 antagonists. The best compound (55, (2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-{[2-(1-piperidinyl)ethyl]amino}-2-(3-thienyl)acetamide) displayed good binding affinity (IC50=30 and 39 nM) toward human monocytes and CHO cell expressing human CCR2b, respectively. Functionally, it

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service