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About This Item
Linear Formula:
CH3CH2CH2CH(COOC2H5)2
CAS Number:
Molecular Weight:
202.25
Beilstein:
510157
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
99%
form
liquid
refractive index
n20/D 1.418 (lit.)
bp
221-222 °C (lit.)
density
0.987 g/mL at 25 °C (lit.)
SMILES string
CCCC(C(=O)OCC)C(=O)OCC
InChI
1S/C10H18O4/c1-4-7-8(9(11)13-5-2)10(12)14-6-3/h8H,4-7H2,1-3H3
InChI key
GRRSDGHTSMJICM-UHFFFAOYSA-N
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Application
Diethyl propylmalonate was used in the synthesis of propylacrylic acid (PAA).
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
197.6 °F - closed cup
Flash Point(C)
92 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Mohamed E H El-Sayed et al.
Journal of controlled release : official journal of the Controlled Release Society, 104(2), 417-427 (2005-06-29)
Limited cytoplasmic delivery of enzyme-susceptible drugs remains a significant challenge facing the development of protein and nucleic acid therapies that act in intracellular compartments. "Smart" pH-responsive, membrane-destabilizing polymers present a new approach to shuttling therapeutic molecules past the endosomal membrane
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Cancer vaccines targeting patient-specific tumor neoantigens have recently emerged as a promising component of the rapidly expanding immunotherapeutic armamentarium. However, neoantigenic peptides typically elicit weak CD8+ T cell responses, and so there is a need for universally applicable vaccine delivery
Brian C Evans et al.
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A platform technology has been developed and tested for delivery of intracellular-acting peptides through electrostatically complexed nanoparticles, or nano-polyplexes, formulated from an anionic endosomolytic polymer and cationic therapeutic peptides. This delivery platform has been initially tested and optimized for delivery
Xi Zhan et al.
Pharmaceutical research, 32(7), 2280-2291 (2015-01-17)
A key step of delivering extracellular agents to its intracellular target is to escape from endosomal/lysosomal compartments, while minimizing the release of digestive enzymes that may compromise cellular functions. In this study, we examined the intracellular distribution of both fluorecent
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