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Key Documents

199222

Sigma-Aldrich

Chromone

99%

Synonym(s):

1-Benzopyran-4-one

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About This Item

Empirical Formula (Hill Notation):
C9H6O2
CAS Number:
Molecular Weight:
146.14
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

99%

mp

55-60 °C (lit.)

functional group

ketone

SMILES string

O=C1C=COc2ccccc12

InChI

1S/C9H6O2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H

InChI key

OTAFHZMPRISVEM-UHFFFAOYSA-N

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General description

The compounds with chromone skeleton exhibits antiradical activities that provide protection against oxidative stress.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Anna Chen et al.
Molecules (Basel, Switzerland), 24(17) (2019-08-25)
Isorhamnetin-3-O-rhamnoside was synthesized by a highly efficient three-enzyme (rhamnosyltransferase, glycine max sucrose synthase and uridine diphosphate (UDP)-rhamnose synthase) cascade using a UDP-rhamnose regeneration system. The rhamnosyltransferase gene (78D1) from Arabidopsis thaliana was cloned, expressed, and characterized in Escherichia coli. The
Miguel Pinto et al.
Pharmaceutics, 11(7) (2019-07-25)
The current pharmacological treatments for Parkinson's disease only offer symptomatic relief to the patients and are based on the administration of levodopa and catechol-O-methyltransferase or monoamine oxidase-B inhibitors (IMAO-B). Since the majority of drug candidates fail in pre- and clinical
Sarvesh Kumar et al.
Bioorganic & medicinal chemistry, 15(8), 2952-2962 (2007-02-27)
The interaction between leukocytes and the vascular endothelial cells (EC) via cellular adhesion molecules plays an important role in various inflammatory and immune diseases. The molecules that block these interactions have been targeted as potential therapeutic targets for acute and
Aleksandra Kładna et al.
Luminescence : the journal of biological and chemical luminescence, 29(7), 846-853 (2014-02-01)
Recent reviews evidence that the naturally occurring compounds containing the chromone skeleton exhibit antiradical activities, providing protection against oxidative stress. The antioxidant activities of 13 new synthesized chromonyl-2,4-thiazolidinediones, chromonyl-2,4-imidazolidinediones and chromonyl-2-thioxoimidzolidine-4-ones were evaluated using in vitro antioxidant assays, including superoxide
Włodzimierz Lewandowski et al.
PloS one, 15(8), e0229477-e0229477 (2020-08-22)
The research was conducted in the "logical series" of seven ligands: chromone, flavone, 3-hydroxyflavone, 3,7-dihydroxyflavone, galangin, kaempferol and quercetin. Each subsequent ligand differs from the previous one, among others by an additional hydroxyl group. The studied chromone derivatives are plant

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