191558
4-Aminobenzyl alcohol
98%
Synonym(s):
4-(Hydroxymethyl)aniline
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About This Item
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Quality Level
Assay
98%
mp
60-65 °C (lit.)
functional group
hydroxyl
storage temp.
2-8°C
SMILES string
Nc1ccc(CO)cc1
InChI
1S/C7H9NO/c8-7-3-1-6(5-9)2-4-7/h1-4,9H,5,8H2
InChI key
AXKGIPZJYUNAIW-UHFFFAOYSA-N
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General description
4-Aminobenzyl alcohol is used as a starting material to synthesize other organic compounds.
Application
4-Aminobenzyl alcohol can be used:
- In the synthesis of 4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutylamino}benzyl ester.
- As a reactant to synthesize cross-azo compounds and cathepsin B cleavable dipeptide linker.
- As a starting material to synthesize hydrogelators for drug delivery applications.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A novel 4-aminobenzyl ester-based carboxy-protecting group for synthesis of atypical peptides by Fmoc-But solid-phase chemistry.
Journal of the Chemical Society. Chemical Communications, 21, 2209-2210 (1995)
The rational design of a peptide-based hydrogel responsive to H 2 S
Chemical Communications (Cambridge, England), 51(97), 17273-17276 (2015)
Chemical communications (Cambridge, England), 47(15), 4364-4366 (2011-03-04)
Nucleic acid templated reactions have attracted significant attention for nucleic acid sensing. Herein we report a general design which extends the potential of nucleic acid templated reactions to unleash the function of a broad diversity of small molecules such as
Improved Methodology for the Synthesis of a Cathepsin B Cleavable Dipeptide Linker, Widely Used in Antibody-Drug Conjugate Research
Tetrahedron Letters, 59(40), 3594-3599 (2018)
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 191, 27-35 (2017-10-06)
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