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P6888

Sigma-Aldrich

6-Phosphogluconic acid trisodium salt

≥95% anhydrous basis

Synonym(s):

D-Gluconate 6-phosphate trisodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H10Na3O10P
CAS Number:
Molecular Weight:
342.08
Beilstein:
3814212
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic (inorganic)

Quality Level

Assay

≥95% anhydrous basis

form

powder

impurities

≤0.2% glucose-6-phosphate

color

light yellow

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 18-21% (anhydrous)

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H13O10P.3Na/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12;;;/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15);;;/q;3*+1/p-3/t2-,3-,4+,5-;;;/m1.../s1

InChI key

CBQSOSFCUWVWAQ-CXKLNRRHSA-K

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Application

6-Phosphogluconic acid has been used in a study to assess a new phosphorylated intermediate in glucose oxidation. It has also been used in a study to investigate direct oxidation of flucose-6-phosphate by animal tissues.

Preparation Note

Prepared enzymatically.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Direct oxidation of glucose-6-phosphate by animal tissues.
F DICKENS et al.
Nature, 166(4209), 33-33 (1950-07-01)
Yasaman Barekatain et al.
Communications biology, 3(1), 328-328 (2020-06-27)
Magnetic resonance (MR) spectroscopy has potential to non-invasively detect metabolites of diagnostic significance for precision oncology. Yet, many metabolites have similar chemical shifts, yielding highly convoluted 1H spectra of intact biological material and limiting diagnostic utility. Here, we show that
A new phosphorylated intermediate in glucose oxidation.
J MACGEE et al.
The Journal of biological chemistry, 210(2), 617-626 (1954-10-01)

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