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P4636

Sigma-Aldrich

Poly-L-glutamic acid sodium salt

suitable for ligand binding assays, Mol wt 3,000-15,000

Synonym(s):

L-Glutamic acid homopolymer sodium salt

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About This Item

CAS Number:
26247-79-0
MDL number:
MFCD00081868
UNSPSC Code:
12352209
NACRES:
NA.26

product name

Poly-L-glutamic acid sodium salt, mol wt 3,000-15,000

form

powder

Quality Level

200

mol wt

3,000-15,000

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

InChI

1S/C15H23N3O10/c16-7(1-4-10(19)20)13(25)17-8(2-5-11(21)22)14(26)18-9(15(27)28)3-6-12(23)24/h7-9H,1-6,16H2,(H,17,25)(H,18,26)(H,19,20)(H,21,22)(H,23,24)(H,27,28)/t7-,8-,9-/m0/s1

InChI key

BUZMZDDKFCSKOT-CIUDSAMLSA-N

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Application


  • Bulk Biopolyelectrolyte Complexes from Homopolypeptides: Solid "Salt Bridges".: Investigates the creation of solid structures from biopolyelectrolyte complexes using Poly-L-glutamic acid sodium salt, emphasizing its potential in creating innovative materials with unique properties (Digby ZA et al., 2023).

  • Polymeric Core-Shell Nanoparticles Prepared by Spontaneous Emulsification Solvent Evaporation and Functionalized by the Layer-by-Layer Method.: This research utilizes Poly-L-glutamic acid sodium salt in the production of core-shell structured nanoparticles, indicating its utility in nanoparticle functionalization and stability (Szczęch M et al., 2020).

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

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Chemical Society reviews, 36(4), 636-649 (2007-03-28)
Polyelectrolyte capsules have recently been introduced as new microscopic vehicles which could have high potential in the biomedical field. In this critical review we give an introduction to the layer-by-layer (LbL) technique which is used to fabricate these polyelectrolyte capsules
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Langmuir : the ACS journal of surfaces and colloids, 28(2), 1545-1551 (2011-12-14)
The interaction of biocompatible polyelectrolytes (chargeable poly(amino acids)) with oxidized starch microgel particles has been studied. The aim was to form a polyelectrolyte complex layer around the outer shell of microgel particles filled with functional ingredients to slow down the
K Szczepanowicz et al.
Langmuir : the ACS journal of surfaces and colloids, 26(15), 12592-12597 (2010-07-08)
The aim of this work was to develop a novel method of preparation of loaded nanosize capsules based on liquid core encapsulation by biocompatible polyelectrolyte (PE) multilayer adsorption, with or without pegylated outermost layer. Using AOT (docusate sodium salt) as
Alexei A Antipov et al.
Advances in colloid and interface science, 111(1-2), 49-61 (2004-12-02)
This review is devoted to a novel type of polymer micro- and nanocapsules. The shell of the capsule is fabricated by alternate adsorption of oppositely charged polyelectrolytes (PEs) onto the surface of colloidal particles. Cores of different nature (organic or

Articles

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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