I4902

Anti-Interferon-α/β Receptor 1 antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-IFN-α/β R1
• MDL number: MFCD03455330
• UNSPSC Code: 51111800
• NACRES: NA.41

Properties

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): flow cytometry: suitable (1-10μg/10⁶ cells); western blot: 0.1-1 μg/mL
• UniProt accession no.: P17181
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... IFNAR1(3454)

Description

General description

Interferon-α/β Receptor 1 is a dimeric, disulfide-linked protein that binds human interferons α and β. This receptor also interacts with Tyr kinase JAK1, and thereby regulates cellular signaling across the membranes . Anti-Interferon-α/β Receptor 1 is specific for recombinant human IFN-α/β R1 and does not react with recombinant human IFN-γ RI and IFN-γ RII.

Immunogen

recombinant human IFN-α/β R1 extracellular domain expressed in Sf21 insect cells.

Application

Anti-Interferon-α/β Receptor 1 antibody is suitable for usein flow cytometry (1-10μg/10⁶ cells) and western blot (0.1-1 μg/mL). Theantibody may also be used for immunoblotting (approx. 135kDa) and indirectimmunofluorescence (using appropriate secondary antibodies).

Physical form

0.1-1 μg/mL Recombinant Human IFN-α/β R1, HeLa humancervical epithelial carcinoma cell line, K562 human chronic myelogenousleukemia cell line.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable