F8182

Faropenem sodium hydrate

≥98% (HPLC)

• Synonym(s): (5R,6S,8R,2′R)-2-(2′-tetrahydrofuryl)-6-hydroxyethylpenem-3-carboxylate sodium salt, ALP 201, Farom, Fropenem, Furopenem, SUN 5555, SY 5555, Wy 49605
• Empirical Formula (Hill Notation): C₁₂H₁₄NNaO₅S · xH₂O
• CAS Number: 122547-49-3
• Molecular Weight: 307.30 (anhydrous basis)
• MDL number: MFCD17215925
• UNSPSC Code: 12352200
• PubChem Substance ID: 329799769
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +120 to +130°, c = 1.0 in water
• storage condition: desiccated
• color: white to light brown
• solubility: H₂O: ≥20 mg/mL
• originator: Daiichi-Sankyo
• storage temp.: −20°C
• SMILES string: O.[Na+].C[C@@H](O)C1C2SC(C3CCCO3)=C(N2C1=O)C([O-])=O
• InChI: 1S/C12H15NO5S.Na.H2O/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6;;/h5-7,11,14H,2-4H2,1H3,(H,16,17);;1H2/q;+1;/p-1/t5-,6-,7+,11-;;/m1../s1
• InChI key: FHSVCMPZCIOKGW-VIDQLUEFSA-M

Description

General description

Faropenem sodium hydrate belongs to the penem group of antibiotics prescribed for oral usage. Enterobacteriaceae bacterial infections with cephalosporin resistance are susceptible to faropenem. Faropenem could be an effective antibiotic to treat urinary tract infections caused by extended-spectrum beta-lactamases (ESBL) producing bacteria.

Biochem/physiol Actions

Faropenem sodium is an ultra-broad spectrum, β-lactamase resistant, β-lactam antibiotic active against both Gram-positive and Gram-negative bacteria.

Features and Benefits

This compound was developed by Daiichi-Sankyo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable