D4630
2,5-Diphenyloxazole
suitable for liquid scintillation spectrometry
Synonym(s):
DPO, PPO
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About This Item
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form
powder
Quality Level
bp
360 °C (lit.)
mp
72-74 °C (lit.)
suitability
suitable for liquid scintillation spectrometry
SMILES string
c1ccc(cc1)-c2cnc(o2)-c3ccccc3
InChI
1S/C15H11NO/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H
InChI key
CNRNYORZJGVOSY-UHFFFAOYSA-N
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General description
2,5-Diphenyloxazole (also known as PPO or p-phenylphenoxazole) is a fluorescent organic compound. It can be also used as an organic scintillator due to its high photoluminescence quantum yield and intriguing luminescent properties. It is widely used as a fluorescent probe or dye in analytical chemistry and biochemistry.
Application
2,5-Diphenyloxazole (PPO) can be used in:
- fluorography techniques for the detection of tritium, tritiated glycopeptides, and 35S labeled proteins.
- liquid scintillation cocktails as primary and secondary fluors.
related product
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
386.6 - 393.8 °F - closed cup
Flash Point(C)
197 - 201 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Study of new luminophores for use in modern scintillation cocktails
Journal of Luminescence, 201, 390-396 (2018)
Two-component molecular materials of 2, 5-diphenyloxazole exhibiting tunable ultraviolet/blue polarized emission, pump-enhanced luminescence, and mechanochromic response
Advanced Functional Materials
, 24, 587-594 (2014)
Wavelength dependant quenching of 2, 5-diphenyloxazole fluorescence by nucleotides
Journal of Fluorescence, 18, 29-34 (2008)
Pharmacology & toxicology, 61(3), 184-190 (1987-09-01)
The oxidative metabolism of 2,5-diphenyloxazole (PPO) is associated with 3-methylcholanthrene inducible cytochrome P-450. The major metabolite formed has m/z of 237, corresponding to hydroxylated PPO. All the possible hydroxylated metabolites of PPO were synthesized and characterized, enabling the assignment of
British journal of clinical pharmacology, 22(3), 263-268 (1986-09-01)
As a substrate for human liver microsomes, ethoxyresorufin appears to be metabolised by a group of cytochrome P450 isoenzymes which are inducible by cigarette smoking. Kinetic studies in microsomes from four human livers indicate that only one enzyme component is
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