90C2
Leukocyte Naphthol AS-D Chloroacetate (Specific Esterase) Kit
Synonym(s):
Leder Stain
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About This Item
NACRES:
NA.47
UNSPSC Code:
12352106
description
Select reagents packaged in gelatin capsules
Quality Level
shelf life
Expiry date on the label.
IVD
for in vitro diagnostic use
dilution
(for histology)
application(s)
hematology
histology
shipped in
wet ice
storage temp.
2-8°C
Application
Esterases are ubiquitous in nature and encompass a series of different enzymes acting upon select substrates. With the 90C2 kit, Naphthol AS-D Chloroacetate is enzymatically hydrolyzed by "specific esterase, " liberating a free naphthol compound. This then couples with a diazonium salt, forming highly colored deposits at sites of enzyme activity. This enzyme is usually considered specific for cells of granulocytic lineage. May be used to detect neutrophils in peripheral blood, bone marrow or tissue sections which have been paraffin embedded.
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Kit Components Only
Product No.
Description
- Dimethyl formamide (9010) 25 mL
- Fast Corinth V Salt (9015) 10 capsules
signalword
Danger
supp_hazards
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - STOT RE 2 Oral
target_organs
Central nervous system
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J Heijmans et al.
Oncogene, 32(9), 1202-1206 (2012-04-04)
Development of colon cancer is a multistep process that is regulated by intrinsic and extrinsic cellular signals. Extrinsic factors include molecular patterns that are derived from either pathogens (PAMPs) or cellular damage (DAMPs). These molecules can promote tumourigenesis by activation
John Zagorski et al.
Journal of immunology (Baltimore, Md. : 1950), 179(11), 7820-7826 (2007-11-21)
Right ventricular (RV) dysfunction is a strong risk factor for poor clinical outcome following pulmonary embolism (PE), the third most prevalent cardiovascular disease. Previous studies in our laboratory demonstrated that RV failure during PE is mediated, in part, by neutrophil-dependant
Chengjie Ma et al.
Molecular medicine reports, 22(1), 483-493 (2020-04-23)
Inactivation of the Hippo pathway protects the myocardium from cardiac ischemic injury. MicroRNAs (miRs) have been reported to play pivotal roles in the progression of myocardial infarction (MI). The present study examined whether miR‑93 could promote angiogenesis and attenuate remodeling
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 90C2-1KT | 04061833647806 |
| 90C2-PART1 | 04061834204022 |