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S5631

Sigma-Aldrich

Silicon dioxide

~99%, 0.5-10 μm (approx. 80% between 1-5 μm)

Synonym(s):

Sand, white quartz, Quartz, Silicon dioxide

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About This Item

Linear Formula:
SiO2
CAS Number:
14808-60-7
Molecular Weight:
60.08
EC Number:
238-878-4
MDL number:
MFCD00011232
UNSPSC Code:
12352300
PubChem Substance ID:
329824458
NACRES:
SB.52

Assay

~99%

form

powder

particle size

0.5-10 μm (approx. 80% between 1-5 μm)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Linkage

Historically called amorphous.

Preparation Note

A naturally occurring microcrystalline silica which has been finely ground.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H372

Precautionary Statements

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Alida Kent et al.
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Yan Liu et al.
Respiratory research, 18(1), 38-38 (2017-02-23)
Myofibroblasts play a major role in the synthesis of extracellular matrix (ECM) and the stimulation of these cells is thought to play an important role in the development of silicosis. The present study was undertaken to investigate the anti-fibrotic effects
Jian-Feng Li et al.
Plant methods, 6(1), 1-1 (2010-02-26)
Research in plant molecular biology involves DNA purification on a daily basis. Although different commercial kits enable convenient extraction of high-quality DNA from E. coli cells, PCR and agarose gel samples as well as plant tissues, each kit is designed
Outi Leppäranta et al.
American journal of respiratory cell and molecular biology, 48(4), 448-455 (2012-12-22)
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis and very few therapeutic options. On the molecular level, patients with IPF have increased amounts of the bone morphogenetic protein (BMP) inhibitor gremlin in their lungs, which
Haijun Liu et al.
American journal of physiology. Lung cellular and molecular physiology, 310(2), L121-L132 (2015-11-27)
Silicosis is a systemic disease caused by inhaling silicon dioxide (SiO2). Phagocytosis of SiO2 in the lungs initiates an inflammatory cascade that results in fibroblast proliferation and migration followed by fibrosis. According to previous data from our laboratory, monocyte chemotactic
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