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IRMM315

4-Deoxynivalenol in acetonitrile

IRMM®, certified reference material

Synonym(s):

Deoxynivalenol solution, 3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one, DON, Vomitoxin

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About This Item

Empirical Formula (Hill Notation):
C15H20O6
CAS Number:
51481-10-8
Molecular Weight:
296.32
EC Number:
200-835-2
MDL number:
MFCD09039270
UNSPSC Code:
41116107
PubChem Substance ID:
329815693
NACRES:
NA.24

grade

certified reference material

Agency

IRMM®

manufacturer/tradename

JRC

application(s)

general analytical

format

matrix material

storage temp.

2-8°C

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O

InChI

1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1

InChI key

LINOMUASTDIRTM-QGRHZQQGSA-N

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General description

Check out our entire range of trichothecene type mycotoxin reference materials

Analysis Note

For more information please see:
IRMM315

Legal Information

IRMM is a registered trademark of European Commission

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup

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Sven Dänicke et al.
Toxicology letters, 220(2), 172-180 (2013-04-23)
The systemic effects of the Fusarium toxin deoxynivalenol (DON) and of bacterial lipopolysaccharides (LPS) were studied in male castrated pigs (40.4 ± 3.7 kg) infused intravenously with either DON or LPS alone (100 μg DON/kg/h, 7.5 μg/LPS/kg/h), or together (100
Brenna M Flannery et al.
Toxicology, 304, 192-198 (2013-01-10)
Consumption of the trichothecene deoxynivalenol (DON) suppresses growth in experimental animals - an adverse effect that was used to establish the tolerable daily intake for this toxin. DON ingestion has been recently found to suppress plasma insulin-like growth factor acid-labile
Xiao Pan et al.
Toxicology and applied pharmacology, 268(2), 201-211 (2013-01-29)
Deoxynivalenol (DON), a trichothecene mycotoxin produced by Fusarium that commonly contaminates food, is capable of activating mononuclear phagocytes of the innate immune system via a process termed the ribotoxic stress response (RSR). To encapture global signaling events mediating RSR, we
Mark Winter et al.
Phytopathology, 103(7), 682-689 (2013-06-14)
Factors limiting trichothecene contamination of mature wheat grains after Fusarium infection are of major interest in crop production. In addition to ear infection, systemic translocation of deoxynivalenol (DON) may contribute to mycotoxin levels in grains after stem base infection with
Silvia W Gratz et al.
Applied and environmental microbiology, 79(6), 1821-1825 (2013-01-15)
Deoxynivalenol (DON) is a potent mycotoxin produced by Fusarium molds and affects intestinal nutrient absorption and barrier function in experimental and farm animals. Free DON and the plant metabolite DON-3-β-d-glucoside (D3G) are frequently found in wheat and maize. D3G is
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