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Lenacil

PESTANAL®, analytical standard

Synonym(s):

3-Cyclohexyl-6,7-dihydro-1H-cyclopentapyrimidine-2,4-(3H,5H)-dione

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About This Item

Empirical Formula (Hill Notation):
C13H18N2O2
CAS Number:
Molecular Weight:
234.29
Beilstein:
751331
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3

InChI

1S/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)

InChI key

ZTMKADLOSYKWCA-UHFFFAOYSA-N

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General description

Lenacil is a pre- and post-emergence herbicide used primarily in suger beet crops to control Capsella bursa-pastoris, Lamium amplexicaule, Veronica persica, Anthemis arvensis, Viola arvensis, Polygonum convolvulus, Brassica napus, Papaver rhoeas and Chenopodium album, which acts by inhibiting photosynthesis.

Application

Lenacil may be used as a reference standard for the determination of the analyte:
  • In water sample by the application of planar chromatography with diode array scanning (TLC-DAD) and high-performance chromatography with diode array detection (HPLC-DAD).
  • In dry matrices such as cereal grain and certain feeding stuffs by gas chromatography/triple quadrupole tandem mass spectrometry (GC–MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Relation of lenacil metabolism with growth inhibition of Acer pseudoplatanus cell suspension.
Blein JP.
Plant Sci. Lett., 29(2-3), 237-242 (1983)
B Kosinkiewicz
Acta microbiologica Polonica, 33(2), 103-110 (1984-01-01)
The phenolic compounds produced by Pseudomonas acidovorans interacted with the herbicide Venzar changing its phytotoxicity. Bioassay with Chlorella vulgaris and lettuce showed that the interaction of the bacterial phenols and Venzar was synergistic or antagonistic depending on the concentration of
S J Pietr
Acta microbiologica Polonica, 30(2), 173-182 (1981-01-01)
The effect of pyramin (1-phenyl-4-amino-5-chloro-piridazone-6) and venzar (3-cyclohexyl-5,6-trimethyleneuracil) on growth, oxygen uptake and nitrogenase activity was examined. The possibilities of herbicide accumulation in cells and binding by mucopolisaccharides were also tested. Stimulation of growth was observed in the presence of
Influence of adjuvants addition on lenacil residues in plant and soil.
Kucharski M, et al.
Polish Journal of Agronomy, 5(5), 39-42 (2011)
K Grancharov et al.
Arzneimittel-Forschung, 36(11), 1660-1663 (1986-11-01)
The effects of 3-cyclohexyl-6,7-dihydro-1H-cyclopentapyrimidine-2,4(3H,5H)-dione (lenacil) on macromolecular synthesis, thymidilate synthetase activity, viability and cell cycle progression were studied using Friend leukemia (FL). P388 and Ehrlich ascites tumor cells in suspension, and its cytogenetic effects were studied in a Salmonella/mammalian microsome

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