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A71352

Sigma-Aldrich

4-Aminophenylacetic acid

98%

Synonym(s):

2-(4-Aminophenyl)acetic acid, 4-Aminobenzeneacetic acid

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About This Item

Linear Formula:
H2NC6H4CH2CO2H
CAS Number:
1197-55-3
Molecular Weight:
151.16
Beilstein:
2208094
EC Number:
214-828-7
MDL number:
MFCD00007916
UNSPSC Code:
12352106
PubChem Substance ID:
24891178
NACRES:
NA.22

Assay

98%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

color

light yellow to tan

mp

201 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Nc1ccc(CC(O)=O)cc1

InChI

1S/C8H9NO2/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5,9H2,(H,10,11)

InChI key

CSEWAUGPAQPMDC-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Douglas C McVey et al.
Digestive diseases and sciences, 50(3), 565-573 (2005-04-07)
A new compound, APAZA, consisting of a molecule of 5-aminosalicylic acid linked to one molecule of 4-aminophenylacetic acid by an azo bond, was testedfor its ability to inhibit acute colitis in rats caused by Clostridium difficile toxin A. When administered
Hongye Zhang et al.
Journal of colloid and interface science, 338(2), 468-473 (2009-07-21)
Monodispersed TiO2 hybrid microspheres were prepared via the hydrolysis of titanium isopropoxide (TTIP) in ethanol solution containing p-aminophenylacetic acid (APA). The effects of the APA:TTIP molar ratio, water content, reaction time and reaction temperature on the morphology of the resultant
C S Temple et al.
The Journal of biological chemistry, 273(1), 20-22 (1998-02-07)
4-Aminophenylacetic acid (4-APAA), a peptide mimic lacking a peptide bond, has been shown to interact with a proton-coupled oligopeptide transporter using a number of different experimental approaches. In addition to inhibiting transport of labeled peptides, these studies show that 4-APAA
Ahmed H Bedair et al.
Acta pharmaceutica (Zagreb, Croatia), 56(3), 273-284 (2006-09-01)
Condensation of 4-aminophenylacetic acid with phthalic anhydride gave (dioxoisoindolin-2-yl)phenylacetic acid (1), which was employed as the key intermediate in the synthesis of title compounds 2-8. The products were characterized by analytical and spectral data (IR, 1H NMR, 13C NMR and
D Meredith et al.
The Journal of physiology, 512 ( Pt 3), 629-634 (1999-01-09)
1. 4-Aminomethylbenzoic acid, a molecule which mimics the special configuration of a dipeptide, competitively inhibits peptide influx in both Xenopus Laevis oocytes expressing rabbit PepT1 and through PepT1 in rat renal brush border membrane vesicles. 2. This molecule is not

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