609978
Hydrogen peroxide-18O2 solution
2-3% in H2O, 90 atom % 18O
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About This Item
Linear Formula:
H218O2
Molecular Weight:
38.01
MDL number:
UNSPSC Code:
12352119
PubChem Substance ID:
NACRES:
NA.12
isotopic purity
90 atom % 18O
concentration
2-3% in H2O
mass shift
M+4
storage temp.
−20°C
SMILES string
[18OH][18OH]
InChI
1S/H2O2/c1-2/h1-2H/i1+2,2+2
InChI key
MHAJPDPJQMAIIY-XPULMUKRSA-N
General description
Hydrogen peroxide-18O2, isotopically labeled analogue of hydrogen peroxide.
Application
18O-labeled H2O2 is used to determine absolute rate and pathway of peroxide formation and decay processes in surface waters of a coastal marine site and also use to measure absolute rates of dark H2O2 production in freshwater systems. It is used to study the acetylcoenzyme A (Ac-CoA) metabolism and potential therapeutic approach for cognitive disabilities on D(16) mouse model of down syndrome.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Andrew W Vermilyea et al.
Environmental science & technology, 44(8), 3066-3072 (2010-03-25)
Photochemical production is usually considered to be the main source of H2O2 in freshwater systems; here we show that significant dark production also occurs. We used isotope-labeled H2O2 as a tracer to simultaneously determine H2O2 production and decay rates in
Xiaojing Liu et al.
Cell, 175(2), 502-513 (2018-09-25)
Acetate is a major nutrient that supports acetyl-coenzyme A (Ac-CoA) metabolism and thus lipogenesis and protein acetylation. However, its source is unclear. Here, we report that pyruvate, the end product of glycolysis and key node in central carbon metabolism, quantitatively generates acetate
Bruno Pinto et al.
Neuron, 108(5), 887-904 (2020-10-08)
Microglia are brain-resident immune cells and regulate mechanisms essential for cognitive functions. Down syndrome (DS), the most frequent cause of genetic intellectual disability, is caused by a supernumerary chromosome 21, containing also genes related to the immune system. In the
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