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533203

Sigma-Aldrich

2-(2-Hydroxy-5-methylphenyl)benzotriazole

97%

Synonym(s):

2-(2H-Benzotriazol-2-yl)-p-cresol

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About This Item

Empirical Formula (Hill Notation):
C13H11N3O
CAS Number:
2440-22-4
Molecular Weight:
225.25
EC Number:
219-470-5
MDL number:
MFCD00022903
UNSPSC Code:
12352005
PubChem Substance ID:
24877544
NACRES:
NA.22
Pricing and availability is not currently available.

Assay

97%

reaction suitability

reaction type: C-C Bond Formation

mp

125.5-129.5 °C (lit.)

SMILES string

Cc1ccc(O)c(c1)-n2nc3ccccc3n2

InChI

1S/C13H11N3O/c1-9-6-7-13(17)12(8-9)16-14-10-4-2-3-5-11(10)15-16/h2-8,17H,1H3

InChI key

MCPKSFINULVDNX-UHFFFAOYSA-N

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Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H410

Hazard Classifications

Aquatic Chronic 1 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX4267
MKCV8168
MKCW6456
MKCT2744
MKCS3196

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Contact allergy to Tinuvin P.
A C de Groot et al.
Contact dermatitis, 9(4), 324-325 (1983-07-01)
Y Ikarashi et al.
Contact dermatitis, 30(4), 226-230 (1994-04-01)
The contact sensitizing potential of 2-(2'-hydroxy-5'-methylphenyl)benzotriazole (Tinuvin P) was investigated using the murine local lymph node assay (LLNA) and the mouse ear swelling test with some modification in the induction procedure (modified MEST). Topical exposure of the ears to Tinuvin
Hiroshi Tokunaga et al.
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, (120)(120), 98-100 (2003-03-18)
2-(2'-hydroxy-5'-methylphenyl)-benzotriazole (HMB) is nominated as the restricted ingredients in cosmetics in Japanese Pharmaceutical Affairs Act. So the analytical method for HMB was investigated by HPLC. After dissolving HMB in cream or oil with tetrahydrofuran and making the constant volume with
Allergic contact dermatitis from an ostomy bag.
E van Hecke et al.
Contact dermatitis, 18(2), 121-122 (1988-02-01)
B Niklasson et al.
Contact dermatitis, 21(5), 330-334 (1989-11-01)
Contact allergy to the UV-absorber 2-(2-hydroxy-5-methylphenyl)benzotriazole (Tinuvin P) was revealed in a patient with wrist dermatitis caused by a plastic watch strap. A high-performance liquid chromatography method was developed and subsequent chemical analysis showed the presence of Tinuvin P in
View All Related Papers

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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