Skip to Content
Merck
All Photos(2)

Documents

197017

Sigma-Aldrich

4-Chloro-3,5-dinitrobenzotrifluoride

98%

Synonym(s):

CDNT, DNT-Cl

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
ClC6H2(NO2)2CF3
CAS Number:
393-75-9
Molecular Weight:
270.55
Beilstein:
1220937
EC Number:
206-889-3
MDL number:
MFCD00007068
UNSPSC Code:
12352100
PubChem Substance ID:
24851818
NACRES:
NA.22

Quality Level

100

Assay

98%

form

solid

mp

50-55 °C (lit.)

solubility

water: insoluble

SMILES string

[O-][N+](=O)c1cc(cc(c1Cl)[N+]([O-])=O)C(F)(F)F

InChI

1S/C7H2ClF3N2O4/c8-6-4(12(14)15)1-3(7(9,10)11)2-5(6)13(16)17/h1-2H

InChI key

HFHAVERNVFNSHL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

4-Chloro-3,5-dinitrobenzotrifluoride was used:
  • as derivatization reagent in determination of amikacin in water samples and amino acids by HPLC
  • in the synthesis of N-(2,6-dinitro-4-trifluoromethylphenyl)aniline derivatives
  • in the synthesis of 4,6-dinitro-2,8-bis(trifluoromethyl)phenothiazine and isopropyl-2,6-dinitro-4-trifluoromethylphenyl sulfide

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H302,H310,H315,H319

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

258.8 °F - closed cup

Flash Point(C)

126 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Barbara Kappes et al.
Future microbiology, 2(4), 409-423 (2007-08-09)
The spread of parasitic resistance has necessitated the development of new drugs and drug targets for the treatment of malaria. Microtubules, which have gained outstanding importance as target molecules for the development of anticancer drugs, are likely to be potent
Reaction of 4-chloro-3, 5-dinitrobenzotrifluoride with aniline derivatives. Substituent effects.
Al-Howsaway HOM, et al.
J. Chem. Res. (M), 2007(9), 509-512 (2007)
C Guastadisegni et al.
Ecotoxicology and environmental safety, 12(2), 105-109 (1986-10-01)
Three short-term studies of 7, 14, and 21 days, respectively, were made to investigate the nature of the anemia induced in rats by 3,5-dinitro-4-chloro-alpha,alpha,alpha-trifluorotoluene (DNCTT). This compound is an intermediate in the synthesis of dinitroaniline herbicides and was detected as
Biren A Patel et al.
Journal of human evolution, 108, 176-198 (2017-06-18)
Songhor is an early Miocene fossil locality in Kenya known for its diverse primate assemblage that includes catarrhine species belonging to the genera Kalepithecus, Limnopithecus, Dendropithecus, Rangwapithecus, and Proconsul. Expeditions to Songhor since the 1930s have recovered unassociated catarrhine postcranial
DERIVATIVES OF 4-CHLORO-3, 5-DINITROBENZOTRIFLUORIDE V. SYNTHESIS OF 4, 6-DINITRO-2, 8-BIS (TRIFLUOROMETHYL) PHENOTHIAZINE (1), ISOPROPYL 2, 6-DINITRO-4-TRIFLUOROMETHYLPHENYL SULFIDE (2) AND BIS (2, 6-DINITRO-4-TRIFLUOROMETHYLPHENYL) DISULFIDE (3).
D' aamico JJ, et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 7(2), 143-148 (1979)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service