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SML3359

TP-040

≥98% (HPLC)

Synonym(s):

N-((1-Methyl-1H-imidazol-4-yl)methyl)-4-(4-methylpiperidin-1-yl)pyrimidin-2-amine

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About This Item

Empirical Formula (Hill Notation):
C15H22N6
CAS Number:
2757254-99-0
Molecular Weight:
286.38
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC(CC1)CCN1C2=CC=NC(NCC3=CN(C)C=N3)=N2

InChI

1S/C15H22N6/c1-12-4-7-21(8-5-12)14-3-6-16-15(19-14)17-9-13-10-20(2)11-18-13/h3,6,10-12H,4-5,7-9H2,1-2H3,(H,16,17,19)

InChI key

PWKAYICUBVNJAZ-UHFFFAOYSA-N

Biochem/physiol Actions

Brain penetrant, potent and selective inhibitor of O-GlcNAcase (OGA).
TP-040 is a brain penetrant, potent and selective inhibitor of O-GlcNAcase (OGA). TP-040 increases the level of O-GlcNAcylated protein in cells.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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