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Merck

SML2240

IU1-47

≥98% (HPLC)

Synonym(s):

1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)ethanone

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About This Item

Empirical Formula (Hill Notation):
C19H23ClN2O
CAS Number:
Molecular Weight:
330.85
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

ClC1=CC=C(N2C(C)=CC(C(CN3CCCCC3)=O)=C2C)C=C1

InChI key

VXQIPRWKLACSKZ-UHFFFAOYSA-N

Biochem/physiol Actions

IU1-47 is a potent and selective inhibitor of the deubiquitinating enzyme UPS14. IU1-47 enhances protein degradation including human wild-type and pathological Tau forms in neurons.
potent and selective inhibitor of the deubiquitinating enzyme UPS14


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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