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SML0309

Sodium phenylbutyrate

≥98% (HPLC), histone deacetylase inhibitor, powder

Synonym(s):

4-PBA, 4-Phenylbutyric acid, 4-phenylbutyrate, Buphenyl, Sodium 4-phenylbutyrate, TriButyrate

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About This Item

Empirical Formula (Hill Notation):
C10H11NaO2
CAS Number:
Molecular Weight:
186.18
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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Product Name

Sodium phenylbutyrate, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: ≥5 mg/mL

storage temp.

room temp

SMILES string

[Na+].[O-]C(=O)CCCc1ccccc1

InChI

1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9;/h1-3,5-6H,4,7-8H2,(H,11,12);/q;+1/p-1

InChI key

VPZRWNZGLKXFOE-UHFFFAOYSA-M

General description

Sodium phenylbutyrate stimulates urinary nitrogen excretion. It is a prodrug, which undergoes β-oxidation to phenylacetate. Sodium phenylbutyrate is used to treat urea cycle disorder. It might be associated with menstrual dysfunction, amenorrhea and painful mucositis of the esophagus and stomach.

Application

Sodium phenylbutyrate has been used as an endoplasmic reticulum (ER) stress inhibitor to study the role of ER stress in the expression of betatrophin.

Biochem/physiol Actions

Sodium phenylbutyrate is a histone deacetylase inhibitor.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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This Item
1614512Y0000808PHR3237
assay

≥98% (HPLC)

assay

-

assay

-

assay

-

form

powder

form

-

form

-

form

-

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

300

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: ≥5 mg/mL

solubility

-

solubility

-

solubility

-

color

white to beige

color

-

color

-

color

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

  1. 水溶液の保存方法に関しての質問です。 他のサイトの同一CAS番号の製品は、水溶液にした場合、すぐに使用するまたは、-20℃で保存しその場合は3か月安定するとありますが、こちらの製品も同様の保存方法でよろしいでしょうか。冷蔵保存での安定性のデータはありますか。

    1 answer
    1. Yes, the information provided by trusted sources, applicable to CAS 1716-12-7 may be applied to this product. Note that not all stability data have been validated. For this product, following reconstitution , stock solutions may be stored for up to 3 months at -20°C in aliquots. No solution stability studies of this material have been conducted at refrigerated temperatures. Please see the link below to review a publication that indicates that suspensions of the therapeutic version of this compound may be quite stable:
      https://pubmed.ncbi.nlm.nih.gov/17617502/

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