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Merck

SCP0195

MOG Protein 35-55, MOG Peptide Fragment human

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About This Item

Empirical Formula (Hill Notation):
C120H179N35O28S1
Molecular Weight:
2591.99
NACRES:
NA.32
UNSPSC Code:
12352202
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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

General description

Myelin oligodendrocyte glycoprotein (MOG) is widely expressed at the extracellular surface of myelin sheaths and oligodendrocytes in the central nervous system. The MOG gene is mapped to human chromosome 6p22.1.

Application

MOG Protein 35-55 is used as an antigen/immunogen to induce anti-MOG antibodies to induce experimental diseases such as experimental autoimmune encephalomyelitis (EAE) for study.

Biochem/physiol Actions

Myelin oligodendrocyte glycoprotein (MOG) is believed to function as an adhesion protein that support myelination of nerves. MOG is studied to understand the mechanisms of diseases such as adrenoleukodystrophy, vanishing white matter disease, multiple sclerosis (MS) and Rubella-induced mental retardation.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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